Water-Soluble Photoinitiators in Biomedical Applications

Light-initiated polymerization processes are currently an important tool in various industrial fields. The advancement of technology has resulted in the use of photopolymerization in various biomedical applications, such as the production of 3D hydrogel structures, the encapsulation of cells, and in...

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Main Authors: Wiktoria Tomal, Joanna Ortyl
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/5/1073
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author Wiktoria Tomal
Joanna Ortyl
author_facet Wiktoria Tomal
Joanna Ortyl
author_sort Wiktoria Tomal
collection DOAJ
description Light-initiated polymerization processes are currently an important tool in various industrial fields. The advancement of technology has resulted in the use of photopolymerization in various biomedical applications, such as the production of 3D hydrogel structures, the encapsulation of cells, and in drug delivery systems. The use of photopolymerization processes requires an appropriate initiating system that, in biomedical applications, must meet additional criteria such as high water solubility, non-toxicity to cells, and compatibility with visible low-power light sources. This article is a literature review on those compounds that act as photoinitiators of photopolymerization processes in biomedical applications. The division of initiators according to the method of photoinitiation was described and the related mechanisms were discussed. Examples from each group of photoinitiators are presented, and their benefits, limitations, and applications are outlined.
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spelling doaj.art-82f27bac47f64d82a32ccbcee3d13a2a2023-11-19T23:44:21ZengMDPI AGPolymers2073-43602020-05-01125107310.3390/polym12051073Water-Soluble Photoinitiators in Biomedical ApplicationsWiktoria Tomal0Joanna Ortyl1Faculty of Chemical Engineering and Technology, Krakow University of Technology, Warszawska 24, 31-155 Krakow, PolandFaculty of Chemical Engineering and Technology, Krakow University of Technology, Warszawska 24, 31-155 Krakow, PolandLight-initiated polymerization processes are currently an important tool in various industrial fields. The advancement of technology has resulted in the use of photopolymerization in various biomedical applications, such as the production of 3D hydrogel structures, the encapsulation of cells, and in drug delivery systems. The use of photopolymerization processes requires an appropriate initiating system that, in biomedical applications, must meet additional criteria such as high water solubility, non-toxicity to cells, and compatibility with visible low-power light sources. This article is a literature review on those compounds that act as photoinitiators of photopolymerization processes in biomedical applications. The division of initiators according to the method of photoinitiation was described and the related mechanisms were discussed. Examples from each group of photoinitiators are presented, and their benefits, limitations, and applications are outlined.https://www.mdpi.com/2073-4360/12/5/1073water-soluble photoinitiatorstype I photoinitiatorstype II photoinitiatorstwo-photon initiators (2PP)photopolymerizationbiomedical applications
spellingShingle Wiktoria Tomal
Joanna Ortyl
Water-Soluble Photoinitiators in Biomedical Applications
Polymers
water-soluble photoinitiators
type I photoinitiators
type II photoinitiators
two-photon initiators (2PP)
photopolymerization
biomedical applications
title Water-Soluble Photoinitiators in Biomedical Applications
title_full Water-Soluble Photoinitiators in Biomedical Applications
title_fullStr Water-Soluble Photoinitiators in Biomedical Applications
title_full_unstemmed Water-Soluble Photoinitiators in Biomedical Applications
title_short Water-Soluble Photoinitiators in Biomedical Applications
title_sort water soluble photoinitiators in biomedical applications
topic water-soluble photoinitiators
type I photoinitiators
type II photoinitiators
two-photon initiators (2PP)
photopolymerization
biomedical applications
url https://www.mdpi.com/2073-4360/12/5/1073
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