Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal Period
Introduction: Enteroviruses (EV) are a common cause of neonatal sepsis especially at the junction of summer and fall. Aim: This study was planned to find the frequency of Enteroviral (EV) sepsis among neonates with clinical sepsis. Materials and Methods: This is a prospective descriptive study....
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-11-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/8813/16434_CE(RA1)_F(T)_PF1(NERK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Introduction: Enteroviruses (EV) are a common cause of neonatal
sepsis especially at the junction of summer and fall.
Aim: This study was planned to find the frequency of Enteroviral
(EV) sepsis among neonates with clinical sepsis.
Materials and Methods: This is a prospective descriptive study.
Rectal and pharyngeal swab samples were taken from all neonates
with clinical sepsis and a control group of neonates with simple
jaundice. EV was confirmed by both cell culture and RT-PCR. Anti
polio antiserum was used to differentiate Polioviruses from Non
Polio EVs (NPEV).
Results: We had 67 neonates with clinical sepsis and 31 cases
of simple jaundice during 105 days. NPEVs were isolated from
2 cases (2.9%) of the sepsis arm and one neonate (3.2%) of the
jaundice group. Polio virus was isolated from 16.2% and 15.3% of
OPV recipients in the sepsis and jaundice group respectively.
Conclusion: Enteroviruses were not a common cause for neonatal
sepsis in Nemazi hospital at the time of this study. OPV vaccinated
neonates commonly pass the vaccine virus in their pharynx and
stool which can be mistaken with NPEV. |
|---|---|
| ISSN: | 2249-782X 0973-709X |