Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal Period
Introduction: Enteroviruses (EV) are a common cause of neonatal sepsis especially at the junction of summer and fall. Aim: This study was planned to find the frequency of Enteroviral (EV) sepsis among neonates with clinical sepsis. Materials and Methods: This is a prospective descriptive study....
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2016-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/8813/16434_CE(RA1)_F(T)_PF1(NERK)_PFA(AK)_PF2(PAG).pdf |
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| author | Mohammad Saeed Sasan Alireza Ataei Nakhaei Abdolvahab Alborzi Mazyar Ziyaeyan |
| author_facet | Mohammad Saeed Sasan Alireza Ataei Nakhaei Abdolvahab Alborzi Mazyar Ziyaeyan |
| author_sort | Mohammad Saeed Sasan |
| collection | DOAJ |
| description | Introduction: Enteroviruses (EV) are a common cause of neonatal
sepsis especially at the junction of summer and fall.
Aim: This study was planned to find the frequency of Enteroviral
(EV) sepsis among neonates with clinical sepsis.
Materials and Methods: This is a prospective descriptive study.
Rectal and pharyngeal swab samples were taken from all neonates
with clinical sepsis and a control group of neonates with simple
jaundice. EV was confirmed by both cell culture and RT-PCR. Anti
polio antiserum was used to differentiate Polioviruses from Non
Polio EVs (NPEV).
Results: We had 67 neonates with clinical sepsis and 31 cases
of simple jaundice during 105 days. NPEVs were isolated from
2 cases (2.9%) of the sepsis arm and one neonate (3.2%) of the
jaundice group. Polio virus was isolated from 16.2% and 15.3% of
OPV recipients in the sepsis and jaundice group respectively.
Conclusion: Enteroviruses were not a common cause for neonatal
sepsis in Nemazi hospital at the time of this study. OPV vaccinated
neonates commonly pass the vaccine virus in their pharynx and
stool which can be mistaken with NPEV. |
| first_indexed | 2024-12-22T02:20:44Z |
| format | Article |
| id | doaj.art-82f296fd644146ada22501a514936653 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-22T02:20:44Z |
| publishDate | 2016-11-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-82f296fd644146ada22501a5149366532022-12-21T18:42:07ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-11-011011SM01SM0210.7860/JCDR/2016/16434.8813Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal PeriodMohammad Saeed Sasan0Alireza Ataei Nakhaei1Abdolvahab Alborzi2Mazyar Ziyaeyan3Associate Professor, Department of Paediatrics, Mashhad University of Medical Sciences, Imam Reza Hospital, Mashhad, Iran.Assistant Professor, Department of Paediatrics, Mashhad University of Medical Sciences, Imam Reza Hospital, Mashhad, Iran.Professor, Department of Paediatrics, Shiraz University of Medical Sciences, Namazi General Hospital, Shiraz, Iran.Professor, Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Namazi General Hospital, Shiraz, Iran. Introduction: Enteroviruses (EV) are a common cause of neonatal sepsis especially at the junction of summer and fall. Aim: This study was planned to find the frequency of Enteroviral (EV) sepsis among neonates with clinical sepsis. Materials and Methods: This is a prospective descriptive study. Rectal and pharyngeal swab samples were taken from all neonates with clinical sepsis and a control group of neonates with simple jaundice. EV was confirmed by both cell culture and RT-PCR. Anti polio antiserum was used to differentiate Polioviruses from Non Polio EVs (NPEV). Results: We had 67 neonates with clinical sepsis and 31 cases of simple jaundice during 105 days. NPEVs were isolated from 2 cases (2.9%) of the sepsis arm and one neonate (3.2%) of the jaundice group. Polio virus was isolated from 16.2% and 15.3% of OPV recipients in the sepsis and jaundice group respectively. Conclusion: Enteroviruses were not a common cause for neonatal sepsis in Nemazi hospital at the time of this study. OPV vaccinated neonates commonly pass the vaccine virus in their pharynx and stool which can be mistaken with NPEV.https://jcdr.net/articles/PDF/8813/16434_CE(RA1)_F(T)_PF1(NERK)_PFA(AK)_PF2(PAG).pdfenterovirusneonatesepsis |
| spellingShingle | Mohammad Saeed Sasan Alireza Ataei Nakhaei Abdolvahab Alborzi Mazyar Ziyaeyan Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal Period Journal of Clinical and Diagnostic Research enterovirus neonate sepsis |
| title | Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal Period |
| title_full | Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal Period |
| title_fullStr | Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal Period |
| title_full_unstemmed | Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal Period |
| title_short | Interference of Vaccine Derived Polio Viruses with Diagnosis of Enteroviral Diseases in Neonatal Period |
| title_sort | interference of vaccine derived polio viruses with diagnosis of enteroviral diseases in neonatal period |
| topic | enterovirus neonate sepsis |
| url | https://jcdr.net/articles/PDF/8813/16434_CE(RA1)_F(T)_PF1(NERK)_PFA(AK)_PF2(PAG).pdf |
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