Quantitative analysis of coronary vessels with optimized intracoronary CT number.
BACKGROUND: Variability in intracoronary computed tomography (CT) number may influence vessel quantification. We confirmed the feasibility of a novel method for measuring vessel diameter and area using coronary CT angiography (CCTA) with an optimized intracoronary CT number, 350 HU. METHODS: We perf...
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| Format: | Article |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3883697?pdf=render |
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| author | Sei Komatsu Teruaki Kamata Atsuko Imai Tomoki Ohara Kazuaki Miyaji Yasuhiko Kobayashi Kazuhisa Kodama |
| author_facet | Sei Komatsu Teruaki Kamata Atsuko Imai Tomoki Ohara Kazuaki Miyaji Yasuhiko Kobayashi Kazuhisa Kodama |
| author_sort | Sei Komatsu |
| collection | DOAJ |
| description | BACKGROUND: Variability in intracoronary computed tomography (CT) number may influence vessel quantification. We confirmed the feasibility of a novel method for measuring vessel diameter and area using coronary CT angiography (CCTA) with an optimized intracoronary CT number, 350 HU. METHODS: We performed intravascular ultrasound (IVUS) imaging in 52 patients with significant stenosis detected by coronary CT angiography targeting 350 HU using a CT number-controlling system. We measured 0-to-0 HU distances in the cross-sectional coronary images of 32 patients. We analyzed the ratio of 0-to-0 HU distances in CT images to media-to-media distances in IVUS images (C:I ratio). The area of ≥0 HU for 103 representative points in the remaining 20 patients was compared to the area of the traced external elastic membrane (EEM) in IVUS images. RESULTS: There was a strong correlation between 0-to-0 HU distance in CT images and media-to-media diameter in IVUS images (r = 0.97, p<0.001). The C:I ratio was 1.1. EEM area was estimated by dividing the area of ≥0 HU by the square of C:I. There was also a strong correlation between the estimated EEM area and the EEM area in IVUS images (r = 0.95, p<0.001). CONCLUSIONS: Media-to-media diameter and EEM area can be estimated by CCTA targeting the optimized intracoronary CT number when blood vessel borders are defined at 0 HU. |
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| id | doaj.art-82f8b739c6c844469dd4b85859419215 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T13:31:15Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj.art-82f8b739c6c844469dd4b858594192152022-12-21T22:59:41ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0191e8531210.1371/journal.pone.0085312Quantitative analysis of coronary vessels with optimized intracoronary CT number.Sei KomatsuTeruaki KamataAtsuko ImaiTomoki OharaKazuaki MiyajiYasuhiko KobayashiKazuhisa KodamaBACKGROUND: Variability in intracoronary computed tomography (CT) number may influence vessel quantification. We confirmed the feasibility of a novel method for measuring vessel diameter and area using coronary CT angiography (CCTA) with an optimized intracoronary CT number, 350 HU. METHODS: We performed intravascular ultrasound (IVUS) imaging in 52 patients with significant stenosis detected by coronary CT angiography targeting 350 HU using a CT number-controlling system. We measured 0-to-0 HU distances in the cross-sectional coronary images of 32 patients. We analyzed the ratio of 0-to-0 HU distances in CT images to media-to-media distances in IVUS images (C:I ratio). The area of ≥0 HU for 103 representative points in the remaining 20 patients was compared to the area of the traced external elastic membrane (EEM) in IVUS images. RESULTS: There was a strong correlation between 0-to-0 HU distance in CT images and media-to-media diameter in IVUS images (r = 0.97, p<0.001). The C:I ratio was 1.1. EEM area was estimated by dividing the area of ≥0 HU by the square of C:I. There was also a strong correlation between the estimated EEM area and the EEM area in IVUS images (r = 0.95, p<0.001). CONCLUSIONS: Media-to-media diameter and EEM area can be estimated by CCTA targeting the optimized intracoronary CT number when blood vessel borders are defined at 0 HU.http://europepmc.org/articles/PMC3883697?pdf=render |
| spellingShingle | Sei Komatsu Teruaki Kamata Atsuko Imai Tomoki Ohara Kazuaki Miyaji Yasuhiko Kobayashi Kazuhisa Kodama Quantitative analysis of coronary vessels with optimized intracoronary CT number. PLoS ONE |
| title | Quantitative analysis of coronary vessels with optimized intracoronary CT number. |
| title_full | Quantitative analysis of coronary vessels with optimized intracoronary CT number. |
| title_fullStr | Quantitative analysis of coronary vessels with optimized intracoronary CT number. |
| title_full_unstemmed | Quantitative analysis of coronary vessels with optimized intracoronary CT number. |
| title_short | Quantitative analysis of coronary vessels with optimized intracoronary CT number. |
| title_sort | quantitative analysis of coronary vessels with optimized intracoronary ct number |
| url | http://europepmc.org/articles/PMC3883697?pdf=render |
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