Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral Replication

Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral Replication

Human cytomegalovirus (HCMV) is a prototypic betaherpesvirus which causes severe manifestations in individuals with impaired or immature immunity. To investigate cytomegalovirus-induced pathogenesis and virus-specific immune responses, mouse cytomegalovirus (MCMV) infections in mice are employed as...

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Bibliographic Details
Main Authors: Mareike Eilbrecht, Vu Thuy Khanh Le-Trilling, Mirko Trilling
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cytomegalovirus
M34
UL34
non-essential
BAC mutagenesis
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00171/full

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