Inpatients in substance use treatment with co-occurring psychiatric disorders: a prospective cohort study of characteristics and relapse predictors
Abstract Background The characteristics of substance use disorder (SUD) inpatients with co-occurring psychiatric disorders (COD) have been scantly described in the extant literature. This study investigated psychological, demographic and substance use characteristics in these patients, along with pr...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-03-01
|
| Series: | BMC Psychiatry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12888-023-04632-z |
| _version_ | 1797863880538456064 |
|---|---|
| author | Helle Wessel Andersson Mats P. Mosti Trond Nordfjaern |
| author_facet | Helle Wessel Andersson Mats P. Mosti Trond Nordfjaern |
| author_sort | Helle Wessel Andersson |
| collection | DOAJ |
| description | Abstract Background The characteristics of substance use disorder (SUD) inpatients with co-occurring psychiatric disorders (COD) have been scantly described in the extant literature. This study investigated psychological, demographic and substance use characteristics in these patients, along with predictors of relapse 3 months post-treatment. Methods Prospective data from a cohort of 611 inpatients were analyzed for demographics, motivation, mental distress, SUD diagnosis, psychiatric diagnoses (ICD-10) and relapse rate at 3 months post-treatment (retention rate = 70%). Results Compared to patients without COD (n = 322), those with COD (n = 289) were younger, had higher mental distress, lower education and higher likelihood of no permanent residence. The relapse rate was also higher in patients with COD (39.8%) relative to patients without COD (26.4%) (OR = 1.85, 95% CI: 1.23–2.78). The relapse rate was particularly high for patients with COD who were diagnosed with cannabis use disorder (53.3%). Multivariate analysis revealed that among patients with COD, relapse was more likely for individuals with a cannabis use disorder (OR = 2.31, 95% CI: 1.34-4.00), and less likely for older ages (OR = 0.97, 95% CI: 0.94-1.00), females (OR = 0.56, 95% CI: 0.33–0.98) and for those with higher intrinsic motivation (OR = 0.58, 95% CI: 0.42–0.81). Conclusion This study showed that among SUD inpatients, those with COD had relatively persistent high levels of mental distress and an increased risk of relapse. Enhanced measures aimed at COD patients’ mental health problems during the inpatient stay, along with close and personalized follow-up after discharge from residential SUD treatment may reduce the probability of relapse in this group. |
| first_indexed | 2024-04-09T22:43:54Z |
| format | Article |
| id | doaj.art-82fe15305fa04a86bbcf14cb294d893d |
| institution | Directory Open Access Journal |
| issn | 1471-244X |
| language | English |
| last_indexed | 2024-04-09T22:43:54Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj.art-82fe15305fa04a86bbcf14cb294d893d2023-03-22T12:00:23ZengBMCBMC Psychiatry1471-244X2023-03-0123111010.1186/s12888-023-04632-zInpatients in substance use treatment with co-occurring psychiatric disorders: a prospective cohort study of characteristics and relapse predictorsHelle Wessel Andersson0Mats P. Mosti1Trond Nordfjaern2Department of Research and Development, Clinic of Substance Use and Addiction Medicine, St. Olavs University HospitalDepartment of Research and Development, Clinic of Substance Use and Addiction Medicine, St. Olavs University HospitalDepartment of Research and Development, Clinic of Substance Use and Addiction Medicine, St. Olavs University HospitalAbstract Background The characteristics of substance use disorder (SUD) inpatients with co-occurring psychiatric disorders (COD) have been scantly described in the extant literature. This study investigated psychological, demographic and substance use characteristics in these patients, along with predictors of relapse 3 months post-treatment. Methods Prospective data from a cohort of 611 inpatients were analyzed for demographics, motivation, mental distress, SUD diagnosis, psychiatric diagnoses (ICD-10) and relapse rate at 3 months post-treatment (retention rate = 70%). Results Compared to patients without COD (n = 322), those with COD (n = 289) were younger, had higher mental distress, lower education and higher likelihood of no permanent residence. The relapse rate was also higher in patients with COD (39.8%) relative to patients without COD (26.4%) (OR = 1.85, 95% CI: 1.23–2.78). The relapse rate was particularly high for patients with COD who were diagnosed with cannabis use disorder (53.3%). Multivariate analysis revealed that among patients with COD, relapse was more likely for individuals with a cannabis use disorder (OR = 2.31, 95% CI: 1.34-4.00), and less likely for older ages (OR = 0.97, 95% CI: 0.94-1.00), females (OR = 0.56, 95% CI: 0.33–0.98) and for those with higher intrinsic motivation (OR = 0.58, 95% CI: 0.42–0.81). Conclusion This study showed that among SUD inpatients, those with COD had relatively persistent high levels of mental distress and an increased risk of relapse. Enhanced measures aimed at COD patients’ mental health problems during the inpatient stay, along with close and personalized follow-up after discharge from residential SUD treatment may reduce the probability of relapse in this group.https://doi.org/10.1186/s12888-023-04632-zSubstance related disordersPsychiatric comorbidityTreatment outcomeCannabis useMotivation |
| spellingShingle | Helle Wessel Andersson Mats P. Mosti Trond Nordfjaern Inpatients in substance use treatment with co-occurring psychiatric disorders: a prospective cohort study of characteristics and relapse predictors BMC Psychiatry Substance related disorders Psychiatric comorbidity Treatment outcome Cannabis use Motivation |
| title | Inpatients in substance use treatment with co-occurring psychiatric disorders: a prospective cohort study of characteristics and relapse predictors |
| title_full | Inpatients in substance use treatment with co-occurring psychiatric disorders: a prospective cohort study of characteristics and relapse predictors |
| title_fullStr | Inpatients in substance use treatment with co-occurring psychiatric disorders: a prospective cohort study of characteristics and relapse predictors |
| title_full_unstemmed | Inpatients in substance use treatment with co-occurring psychiatric disorders: a prospective cohort study of characteristics and relapse predictors |
| title_short | Inpatients in substance use treatment with co-occurring psychiatric disorders: a prospective cohort study of characteristics and relapse predictors |
| title_sort | inpatients in substance use treatment with co occurring psychiatric disorders a prospective cohort study of characteristics and relapse predictors |
| topic | Substance related disorders Psychiatric comorbidity Treatment outcome Cannabis use Motivation |
| url | https://doi.org/10.1186/s12888-023-04632-z |
| work_keys_str_mv | AT hellewesselandersson inpatientsinsubstanceusetreatmentwithcooccurringpsychiatricdisordersaprospectivecohortstudyofcharacteristicsandrelapsepredictors AT matspmosti inpatientsinsubstanceusetreatmentwithcooccurringpsychiatricdisordersaprospectivecohortstudyofcharacteristicsandrelapsepredictors AT trondnordfjaern inpatientsinsubstanceusetreatmentwithcooccurringpsychiatricdisordersaprospectivecohortstudyofcharacteristicsandrelapsepredictors |