Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination.
The recombination activity of Escherichia coli (E. coli) RecA protein reflects an evolutionary balance between the positive and potentially deleterious effects of recombination. We have perturbed that balance, generating RecA variants exhibiting improved recombination functionality via random mutage...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-06-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4457935?pdf=render |