The effect of viola odorata syrup on anxiety in postmenopausal women: A randomized clinical trial

Background & Aim: Anxiety is one of the most important psychological problems during the menopausal period. Anxiety can affect the health and quality of life of postmenopausal women. The purpose of this study was to investigate the effect of viola odorata syrup on anxiety among postmenopausal wo...

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Main Authors: Fatemeh Lotfi, Fatemeh Zahra Karimi, Seyed Reza Mazloum, Mahdi Yousefi, Hasan Rakhshande
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2021-04-01
Series:حیات
Subjects:
Online Access:http://hayat.tums.ac.ir/article-1-3972-en.html
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author Fatemeh Lotfi
Fatemeh Zahra Karimi
Seyed Reza Mazloum
Mahdi Yousefi
Hasan Rakhshande
author_facet Fatemeh Lotfi
Fatemeh Zahra Karimi
Seyed Reza Mazloum
Mahdi Yousefi
Hasan Rakhshande
author_sort Fatemeh Lotfi
collection DOAJ
description Background & Aim: Anxiety is one of the most important psychological problems during the menopausal period. Anxiety can affect the health and quality of life of postmenopausal women. The purpose of this study was to investigate the effect of viola odorata syrup on anxiety among postmenopausal women. Methods & Materials: This study is a triple blind clinical trial that was performed on 84 postmenopausal women referred to health centers in Mashhad in 2019. In both groups, postmenopausal women received 5 ml of viola odorata or placebo syrup twice a day for one month. Before and after the intervention, anxiety was assessed using the Depression, Anxiety and Stress scale-21. Data was analyzed using the SPSS software version 25 and Mann-Whitney, Chi-square and Fisherchr('39')s exact tests. Results: Before the intervention, there was no significant difference in women’s anxiety levels between viola odorata group and placebo group, and the two groups were homogeneous (P=0.084). After the intervention, there was a significant difference between the two groups (P=0.004). The corrected average was 3.61±3.02 (2.9-4.2, CI95%) for the violet group and 7.63±3.60 (6.9-8.3, CI95%) for the placebo group. Also, after the intervention the anxiety score decreased in the viola odorata group, and increased in the placebo group. The Mann-Whitney U test showed a significant difference (P<0.001). Conclusion: According to the results of the present study, viola odorata syrup decreased anxiety in postmenopausal women. Therefore, it can be used as a complementary treatment along with chemical therapies to reduce anxiety in postmenopausal women. Clinical trial registry: IRCT20180514039660N1
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spelling doaj.art-8304f8f5e8d44abc8ed80d43f4f0e5ed2022-12-21T18:34:58ZfasTehran University of Medical Sciencesحیات1735-22152008-188X2021-04-012714558The effect of viola odorata syrup on anxiety in postmenopausal women: A randomized clinical trialFatemeh Lotfi0Fatemeh Zahra Karimi1Seyed Reza Mazloum2Mahdi Yousefi3Hasan Rakhshande4 Dept. of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran Dept. of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran; Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Dept. of Medical Surgical Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran; Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Dept. of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Dept. of Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Medicinal Plants Pharmacological Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Background & Aim: Anxiety is one of the most important psychological problems during the menopausal period. Anxiety can affect the health and quality of life of postmenopausal women. The purpose of this study was to investigate the effect of viola odorata syrup on anxiety among postmenopausal women. Methods & Materials: This study is a triple blind clinical trial that was performed on 84 postmenopausal women referred to health centers in Mashhad in 2019. In both groups, postmenopausal women received 5 ml of viola odorata or placebo syrup twice a day for one month. Before and after the intervention, anxiety was assessed using the Depression, Anxiety and Stress scale-21. Data was analyzed using the SPSS software version 25 and Mann-Whitney, Chi-square and Fisherchr('39')s exact tests. Results: Before the intervention, there was no significant difference in women’s anxiety levels between viola odorata group and placebo group, and the two groups were homogeneous (P=0.084). After the intervention, there was a significant difference between the two groups (P=0.004). The corrected average was 3.61±3.02 (2.9-4.2, CI95%) for the violet group and 7.63±3.60 (6.9-8.3, CI95%) for the placebo group. Also, after the intervention the anxiety score decreased in the viola odorata group, and increased in the placebo group. The Mann-Whitney U test showed a significant difference (P<0.001). Conclusion: According to the results of the present study, viola odorata syrup decreased anxiety in postmenopausal women. Therefore, it can be used as a complementary treatment along with chemical therapies to reduce anxiety in postmenopausal women. Clinical trial registry: IRCT20180514039660N1http://hayat.tums.ac.ir/article-1-3972-en.htmlwomenanxietyviola odoratamenopauseiran
spellingShingle Fatemeh Lotfi
Fatemeh Zahra Karimi
Seyed Reza Mazloum
Mahdi Yousefi
Hasan Rakhshande
The effect of viola odorata syrup on anxiety in postmenopausal women: A randomized clinical trial
حیات
women
anxiety
viola odorata
menopause
iran
title The effect of viola odorata syrup on anxiety in postmenopausal women: A randomized clinical trial
title_full The effect of viola odorata syrup on anxiety in postmenopausal women: A randomized clinical trial
title_fullStr The effect of viola odorata syrup on anxiety in postmenopausal women: A randomized clinical trial
title_full_unstemmed The effect of viola odorata syrup on anxiety in postmenopausal women: A randomized clinical trial
title_short The effect of viola odorata syrup on anxiety in postmenopausal women: A randomized clinical trial
title_sort effect of viola odorata syrup on anxiety in postmenopausal women a randomized clinical trial
topic women
anxiety
viola odorata
menopause
iran
url http://hayat.tums.ac.ir/article-1-3972-en.html
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