Cyclodextrin Complexation of Fenofibrate by Co-Grinding Method and Monitoring the Process Using Complementary Analytical Tools

Cyclodextrin Complexation of Fenofibrate by Co-Grinding Method and Monitoring the Process Using Complementary Analytical Tools

Solvent-free preparation types for cyclodextrin complexation, such as co-grinding, are technologies desired by the industry. However, in-depth analytical evaluation of the process and detailed characterization of intermediate states of the complexes are still lacking in areas. In our work, we aimed...

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Bibliographic Details
Main Authors: Balázs Attila Kondoros, Ottó Berkesi, Zsolt Tóth, Zoltán Aigner, Rita Ambrus, Ildikó Csóka
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
DIMEB
molecular complexation
solvent-free method
XRPD
DSC
FT-IR
Online Access:https://www.mdpi.com/1999-4923/14/7/1329

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