Identification of Broad-Genotype HPV L2 Neutralization Site for Pan-HPV Vaccine Development by a Cross-Neutralizing Antibody.

Identification of Broad-Genotype HPV L2 Neutralization Site for Pan-HPV Vaccine Development by a Cross-Neutralizing Antibody.

Human Papillomavirus (HPV), a non-enveloped, double-stranded DNA virus, is responsible for 5% of human cancers. The HPV capsid consists of major and minor structural proteins, L1 and L2. L1 proteins form an icosahedral shell with building blocks of the pentameric capsomere, and one L2 molecule exten...

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Bibliographic Details
Main Authors: Daning Wang, Zhihai Li, Jieqiong Xiao, Junqi Wang, Li Zhang, Yajing Liu, Fei Fan, Lu Xin, Minxi Wei, Zhibo Kong, Hai Yu, Ying Gu, Jun Zhang, Shaowei Li, Ningshao Xia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4408011?pdf=render

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