Role and significance of c-KIT receptor tyrosine kinase in cancer: A review

Role and significance of c-KIT receptor tyrosine kinase in cancer: A review

c-kit is a classical proto-oncogene that encodes a receptor tyrosine kinase (RTK) that responds to stem cell factor (SCF). C-KIT signaling is a critical regulator of cell proliferation, survival, and migration and is implicated in several physiological processes, including pigmentation, hematopoies...

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Bibliographic Details
Main Authors:	Emana Sheikh, Tony Tran, Semir Vranic, Arkene Levy, R. Daniel Bonfil
Format:	Article
Language:	English
Published:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022-09-01
Series:	Biomolecules & Biomedicine
Subjects:	c-KIT CD117 cancer receptor tyrosine kinases stem cell factor receptor
Online Access:	https://www.bjbms.org/ojs/index.php/bjbms/article/view/7399

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