The Effect of Hypertonic Saline on mRNA of Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Polymorphonuclear Cells

The Effect of Hypertonic Saline on mRNA of Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Polymorphonuclear Cells

Background: Hypertonic saline is often used to resuscitate patients experiencing shock. In such conditions, polymorphonuclear cells and Toll-like receptors (TLRs) form an essential part of early induced innate immunity. Objective: To investigate the immunomodulatory effect of hypertonic saline on po...

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Bibliographic Details
Main Authors: Sung-Hyuk Choi, MD, PhD, Young-Hoon Yoon, MD, PhD, Jung-Youn Kim, MD, PhD, Sung-Woo Moon, MD, PhD, Young-Duck Cho, MD, PhD, Ji-Won Yeom
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Current Therapeutic Research
Subjects:
cytokine
hypertonic saline solution
immune
inflammation
neutrophil
Toll-like receptor 4
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X14000125

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