Looking beyond year 1 in the molecular era of pediatric brain tumor diagnosis: confirmatory testing of germline variants found on tumor sequencing

Looking beyond year 1 in the molecular era of pediatric brain tumor diagnosis: confirmatory testing of germline variants found on tumor sequencing

PurposeSomatic molecular profiling of pediatric brain tumors aids with the diagnosis and treatment of patients with a variety of high- and low-grade central nervous system neoplasms. Here, we report follow-up targeted germline evaluation for patients with possible germline variants following tumor o...

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Bibliographic Details
Main Authors: Brittany L. Greene, Shannon M. Stasi, Michelle A. Ting, Natalie Waligorski, Bonnie L. Cole, Christina M. Lockwood, Vera A. Paulson, Jillian G. Buchan, Amy Lee, Jeffrey G. Ojemann, Richard G. Ellenbogen, Jeffrey Stevens, Sarah E. S. Leary
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Oncology
Subjects:
childhood cancer
brain tumor
molecular testing
next-generation sequencing
germline
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1338022/full

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