Percutaneous nephrostomy in cervical cancer patients: a retrospective analysis
OBJECTIVES: To evaluate the outcome of patients with cervical carcinoma submitted to percutaneous nephrostomy due to malignant ureteral obstruction. MATERIAL AND METHODS: Retrospective cohort study with data obtained from medical records of patients diagnosed with cervical carcinoma with re...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Oncologia Clínica, Sociedade Brasileira de Cirurgia Clínica and Sociedade Brasileira de Radioterapia
2023-09-01
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| Series: | Brazilian Journal of Oncology |
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| Online Access: | https://www.brazilianjournalofoncology.com.br/details/255/en-US/percutaneous-nephrostomy-in-cervical-cancer-patients--a-retrospective-analysis |
| _version_ | 1797346370217050112 |
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| author | Deborah Pinagé Alves de Lima Carolina do Nascimento Matias Teixeira Marilia de Brito Abath Fernando Antonio Nunes Raposo Silvia Borges Fontan |
| author_facet | Deborah Pinagé Alves de Lima Carolina do Nascimento Matias Teixeira Marilia de Brito Abath Fernando Antonio Nunes Raposo Silvia Borges Fontan |
| author_sort | Deborah Pinagé Alves de Lima |
| collection | DOAJ |
| description | OBJECTIVES: To evaluate the outcome of patients with cervical carcinoma submitted to percutaneous nephrostomy due to malignant ureteral obstruction.
MATERIAL AND METHODS: Retrospective cohort study with data obtained from medical records of patients diagnosed with cervical carcinoma with renal dysfunction (AKIN = stage 2) undergoing PCN for malignant obstructive uropathy between January 2019 and December 2020 at a tertiary hospital in Recife, Brazil.
RESULTS: We evaluated 31 patients submitted to percutaneous nephrostomy. Median age was 50 years, and the majority of women were non-white with an elementary education. Twenty-one patients required hemodialysis before the procedure, and 61.9% of them recovered renal function after nephrostomy. Bleeding and nephrostomytube displacement were the leading causes of complications in the first 30 days (69%). Median overall survival after the procedure was 8.7 months. Survival was significantly worse in patients with anemia, ECOG performance status = 2 (p=0.04), pre-nephrostomy dialysis (p=0.01), and not recovery of renal function after PCN.
CONCLUSIONS: Performing urinary diversion through percutaneous nephrostomy seems to offer greater benefits in patients with better functionality. Given the morbidity and complications inherent to percutaneous nephrostomy, the profile of patients who benefit most from the procedureremains unclear. Referrals for the procedure must be individualized and consider the patient's desire, treatment perspectives, and functionality. |
| first_indexed | 2024-03-08T11:32:30Z |
| format | Article |
| id | doaj.art-83132c5a00194d1ba1fd7be7ab151c31 |
| institution | Directory Open Access Journal |
| issn | 2526-8732 |
| language | English |
| last_indexed | 2024-03-08T11:32:30Z |
| publishDate | 2023-09-01 |
| publisher | Sociedade Brasileira de Oncologia Clínica, Sociedade Brasileira de Cirurgia Clínica and Sociedade Brasileira de Radioterapia |
| record_format | Article |
| series | Brazilian Journal of Oncology |
| spelling | doaj.art-83132c5a00194d1ba1fd7be7ab151c312024-01-25T17:27:37ZengSociedade Brasileira de Oncologia Clínica, Sociedade Brasileira de Cirurgia Clínica and Sociedade Brasileira de RadioterapiaBrazilian Journal of Oncology2526-87322023-09-011910.5935/2526-8732.20230393Percutaneous nephrostomy in cervical cancer patients: a retrospective analysisDeborah Pinagé Alves de Lima0Carolina do Nascimento Matias Teixeira1Marilia de Brito Abath2Fernando Antonio Nunes Raposo3Silvia Borges Fontan4Hospital Barão de Lucena, Internal Medicine - Recife - Pernambuco - BrazilHospital Barão de Lucena, Internal Medicine - Recife - Pernambuco - BrazilHospital Barão de Lucena, Internal Medicine - Recife - Pernambuco - BrazilHospital Barão de Lucena, Internal Medicine - Recife - Pernambuco - BrazilHospital Barão de Lucena, Internal Medicine - Recife - Pernambuco - BrazilOBJECTIVES: To evaluate the outcome of patients with cervical carcinoma submitted to percutaneous nephrostomy due to malignant ureteral obstruction. MATERIAL AND METHODS: Retrospective cohort study with data obtained from medical records of patients diagnosed with cervical carcinoma with renal dysfunction (AKIN = stage 2) undergoing PCN for malignant obstructive uropathy between January 2019 and December 2020 at a tertiary hospital in Recife, Brazil. RESULTS: We evaluated 31 patients submitted to percutaneous nephrostomy. Median age was 50 years, and the majority of women were non-white with an elementary education. Twenty-one patients required hemodialysis before the procedure, and 61.9% of them recovered renal function after nephrostomy. Bleeding and nephrostomytube displacement were the leading causes of complications in the first 30 days (69%). Median overall survival after the procedure was 8.7 months. Survival was significantly worse in patients with anemia, ECOG performance status = 2 (p=0.04), pre-nephrostomy dialysis (p=0.01), and not recovery of renal function after PCN. CONCLUSIONS: Performing urinary diversion through percutaneous nephrostomy seems to offer greater benefits in patients with better functionality. Given the morbidity and complications inherent to percutaneous nephrostomy, the profile of patients who benefit most from the procedureremains unclear. Referrals for the procedure must be individualized and consider the patient's desire, treatment perspectives, and functionality.https://www.brazilianjournalofoncology.com.br/details/255/en-US/percutaneous-nephrostomy-in-cervical-cancer-patients--a-retrospective-analysisuterine cervical neoplasmshydronephrosis, ureteral obstructionurinary diversionnephrostomy, percutaneous |
| spellingShingle | Deborah Pinagé Alves de Lima Carolina do Nascimento Matias Teixeira Marilia de Brito Abath Fernando Antonio Nunes Raposo Silvia Borges Fontan Percutaneous nephrostomy in cervical cancer patients: a retrospective analysis Brazilian Journal of Oncology uterine cervical neoplasms hydronephrosis, ureteral obstruction urinary diversion nephrostomy, percutaneous |
| title | Percutaneous nephrostomy in cervical cancer
patients: a retrospective analysis |
| title_full | Percutaneous nephrostomy in cervical cancer
patients: a retrospective analysis |
| title_fullStr | Percutaneous nephrostomy in cervical cancer
patients: a retrospective analysis |
| title_full_unstemmed | Percutaneous nephrostomy in cervical cancer
patients: a retrospective analysis |
| title_short | Percutaneous nephrostomy in cervical cancer
patients: a retrospective analysis |
| title_sort | percutaneous nephrostomy in cervical cancer patients a retrospective analysis |
| topic | uterine cervical neoplasms hydronephrosis, ureteral obstruction urinary diversion nephrostomy, percutaneous |
| url | https://www.brazilianjournalofoncology.com.br/details/255/en-US/percutaneous-nephrostomy-in-cervical-cancer-patients--a-retrospective-analysis |
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