Radiomics in pancreatic ductal adenocarcinoma: a state of art review

Abstract. Radiomics analysis extracts a large number of features from conventional radiological cross-sectional images that were traditionally undetectable by the naked human eye. It identifies tumor heterogeneity in a comprehensive and noninvasive way, reflecting the biological behaviour of lesions...

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Main Authors: Ming He, MD, Huadan Xue, MD, Zhengyu Jin, MD
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2020-12-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000062
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author Ming He, MD
Huadan Xue, MD
Zhengyu Jin, MD
author_facet Ming He, MD
Huadan Xue, MD
Zhengyu Jin, MD
author_sort Ming He, MD
collection DOAJ
description Abstract. Radiomics analysis extracts a large number of features from conventional radiological cross-sectional images that were traditionally undetectable by the naked human eye. It identifies tumor heterogeneity in a comprehensive and noninvasive way, reflecting the biological behaviour of lesions, and thus assists in clinical diagnosis and treatment evaluation. This review describes the radiomics approach and its uses in the evaluation of pancreatic ductal adenocarcinoma (PDAC). This discipline holds the potential to characterize lesions more accurately, assesses the primary tumour and predicts the response to therapy and prognosis in PDAC. Existing studies have provided significant insights into the application of radiomics in managing the PDAC. However, a variety of challenges, including data quality and quantity, imaging segmentation, and the standardization of the radiomics process need to be solved before its widespread clinical implementation.
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spelling doaj.art-831a8198611d44c0a21533a78203513c2022-12-21T18:39:02ZengWolters Kluwer Health/LWWJournal of Pancreatology2096-56642577-35772020-12-013419520010.1097/JP9.0000000000000062202012000-00005Radiomics in pancreatic ductal adenocarcinoma: a state of art reviewMing He, MDHuadan Xue, MDZhengyu Jin, MDAbstract. Radiomics analysis extracts a large number of features from conventional radiological cross-sectional images that were traditionally undetectable by the naked human eye. It identifies tumor heterogeneity in a comprehensive and noninvasive way, reflecting the biological behaviour of lesions, and thus assists in clinical diagnosis and treatment evaluation. This review describes the radiomics approach and its uses in the evaluation of pancreatic ductal adenocarcinoma (PDAC). This discipline holds the potential to characterize lesions more accurately, assesses the primary tumour and predicts the response to therapy and prognosis in PDAC. Existing studies have provided significant insights into the application of radiomics in managing the PDAC. However, a variety of challenges, including data quality and quantity, imaging segmentation, and the standardization of the radiomics process need to be solved before its widespread clinical implementation.http://journals.lww.com/10.1097/JP9.0000000000000062
spellingShingle Ming He, MD
Huadan Xue, MD
Zhengyu Jin, MD
Radiomics in pancreatic ductal adenocarcinoma: a state of art review
Journal of Pancreatology
title Radiomics in pancreatic ductal adenocarcinoma: a state of art review
title_full Radiomics in pancreatic ductal adenocarcinoma: a state of art review
title_fullStr Radiomics in pancreatic ductal adenocarcinoma: a state of art review
title_full_unstemmed Radiomics in pancreatic ductal adenocarcinoma: a state of art review
title_short Radiomics in pancreatic ductal adenocarcinoma: a state of art review
title_sort radiomics in pancreatic ductal adenocarcinoma a state of art review
url http://journals.lww.com/10.1097/JP9.0000000000000062
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AT huadanxuemd radiomicsinpancreaticductaladenocarcinomaastateofartreview
AT zhengyujinmd radiomicsinpancreaticductaladenocarcinomaastateofartreview