Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial
Background: Melaleuca alternifolia (tea tree) essential oil has been traditionally used in the ayurvedic system of medicine for healing burns, infections and seborrheic dermatitis. But yet, no controlled human study has determined its efficacy. Objective: The goal of the current study was to compare...
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| Format: | Article |
| Language: | English |
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Institue of Medicinal Plants, ACECR
2014-09-01
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| Series: | Journal of Medicinal Plants |
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| Online Access: | http://jmp.ir/article-1-627-en.html |
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| author | A Beheshti Roy B Tavakoli-far H Fallah Huseini P Tousi N Shafigh M Rahimzadeh |
| author_facet | A Beheshti Roy B Tavakoli-far H Fallah Huseini P Tousi N Shafigh M Rahimzadeh |
| author_sort | A Beheshti Roy |
| collection | DOAJ |
| description | Background: Melaleuca alternifolia (tea tree) essential oil has been traditionally used in the ayurvedic system of medicine for healing burns, infections and seborrheic dermatitis. But yet, no controlled human study has determined its efficacy. Objective: The goal of the current study was to compare the efficacy of 5% tea tree essential oil (TTO) gel with placebo in the treatment of mild to moderate facial seborrheic dermatitis. Methods: Fifty four patients with mild to moderate facial seborrheic dermatitis reffered to Skin Diseases Research Center, in the Qazvin city, Iran, were randomly divided into two groups and treated with either 5% TTO gel or placebo three times daily for 4 weeks. The patients follow-ups were conducted in both groups after 2 and 4 weeks with evaluating of erythema, scaling, itching and greasy crusts. Results: Forty two patients completed the treatment course. There were significant differences between the TTO and placebo groups in the improvement of erythema, scaling, itching and greasy crusts (p < 0.05). Allergic side - effects were seen in neither group. Conclusions: 5% TTO gel is effective in the treatment of mild to moderate facial seborrheic dermatitis. |
| first_indexed | 2024-12-22T02:23:20Z |
| format | Article |
| id | doaj.art-831de87e6bd34fe58245ccf97ba33eec |
| institution | Directory Open Access Journal |
| issn | 2717-204X 2717-2058 |
| language | English |
| last_indexed | 2024-12-22T02:23:20Z |
| publishDate | 2014-09-01 |
| publisher | Institue of Medicinal Plants, ACECR |
| record_format | Article |
| series | Journal of Medicinal Plants |
| spelling | doaj.art-831de87e6bd34fe58245ccf97ba33eec2022-12-21T18:42:05ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582014-09-0113512632Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical TrialA Beheshti Roy0B Tavakoli-far1H Fallah Huseini2P Tousi3N Shafigh4M Rahimzadeh5 Dermatology Department, Boali Hospital, Qazvin University of Medical Science, Qazvin, Iran Physiology and Pharmacology Department, Alborz University of Medical Science, Karaj, Iran Pharmacology & Applied Medicine Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran Dermatology Department, Boali Hospital, Qazvin University of Medical Science, Qazvin, Iran Dermatology Department, Boali Hospital, Qazvin University of Medical Science, Qazvin, Iran Department of Social Determination of Health Research Center, Alborz University of Medical Science, Karaj, Iran Background: Melaleuca alternifolia (tea tree) essential oil has been traditionally used in the ayurvedic system of medicine for healing burns, infections and seborrheic dermatitis. But yet, no controlled human study has determined its efficacy. Objective: The goal of the current study was to compare the efficacy of 5% tea tree essential oil (TTO) gel with placebo in the treatment of mild to moderate facial seborrheic dermatitis. Methods: Fifty four patients with mild to moderate facial seborrheic dermatitis reffered to Skin Diseases Research Center, in the Qazvin city, Iran, were randomly divided into two groups and treated with either 5% TTO gel or placebo three times daily for 4 weeks. The patients follow-ups were conducted in both groups after 2 and 4 weeks with evaluating of erythema, scaling, itching and greasy crusts. Results: Forty two patients completed the treatment course. There were significant differences between the TTO and placebo groups in the improvement of erythema, scaling, itching and greasy crusts (p < 0.05). Allergic side - effects were seen in neither group. Conclusions: 5% TTO gel is effective in the treatment of mild to moderate facial seborrheic dermatitis.http://jmp.ir/article-1-627-en.htmlmelaleuca alternifoliafacial seborrheic dermatitistea tree oil geltopical treatment |
| spellingShingle | A Beheshti Roy B Tavakoli-far H Fallah Huseini P Tousi N Shafigh M Rahimzadeh Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial Journal of Medicinal Plants melaleuca alternifolia facial seborrheic dermatitis tea tree oil gel topical treatment |
| title | Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial |
| title_full | Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial |
| title_fullStr | Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial |
| title_full_unstemmed | Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial |
| title_short | Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial |
| title_sort | efficacy of melaleuca alternifolia essential oil in the treatment of facial seborrheic dermatitis a double blind randomized placebo controlled clinical trial |
| topic | melaleuca alternifolia facial seborrheic dermatitis tea tree oil gel topical treatment |
| url | http://jmp.ir/article-1-627-en.html |
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