Nobel prize winners Arvid Carlsson, Paul Greengard and Eric Kandel: the research of signal transduction in the nervous system
For many decades, scientists have tried to unravel the mysteries of the nervous system – the complex phenomenon that receives messages, processes information, and sends signals to the rest of the body. The most important scientific discoveries of the 19th and the 20th centuries paved the way for the...
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2023-04-01
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| Series: | The Ukrainian Biochemical Journal |
| Subjects: | |
| Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2023/06/Danylova_TV_95_2.pdf |
| _version_ | 1797654503297646592 |
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| author | T. V. Danylova S. V. Komisarenko |
| author_facet | T. V. Danylova S. V. Komisarenko |
| author_sort | T. V. Danylova |
| collection | DOAJ |
| description | For many decades, scientists have tried to unravel the mysteries of the nervous system – the complex phenomenon that receives messages, processes information, and sends signals to the rest of the body. The most important scientific discoveries of the 19th and the 20th centuries paved the way for the 2000 Nobel Prize in Physiology or Medicine awarded to Arvid Carlsson, Paul Greengard and Eric Kandel “for their discoveries concerning signal transduction in the nervous system”. So, the beginning of the new millennium was “marked” by pioneering research into the chemical transmission of signals in the central nervous system, which created the foundation for a deeper understanding of the mediatory role of dopamine, the processes of slow synaptic transmission, short-term and long-term memory, and the mechanisms of action of antipsychotic and antidepressant drugs. The paper aims to outline the main stages of scientific activities of a Swedish neuropharmacologist Per Arvid Emil Carlsson and the American neurobiologists Paul Greengard and Eric Richard Kandel. |
| first_indexed | 2024-03-11T17:00:25Z |
| format | Article |
| id | doaj.art-83203a39fab74bd3ab3345b931e0d154 |
| institution | Directory Open Access Journal |
| issn | 2409-4943 2413-5003 |
| language | English |
| last_indexed | 2024-03-11T17:00:25Z |
| publishDate | 2023-04-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | The Ukrainian Biochemical Journal |
| spelling | doaj.art-83203a39fab74bd3ab3345b931e0d1542023-10-20T11:00:38ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryThe Ukrainian Biochemical Journal2409-49432413-50032023-04-0195210611610.15407/ubj95.02.106Nobel prize winners Arvid Carlsson, Paul Greengard and Eric Kandel: the research of signal transduction in the nervous systemT. V. Danylova0https://orcid.org/0000-0002-0297-9473S. V. Komisarenko1https://orcid.org/0000-0002-3244-3194Institute of Social and Political Psychology, National Academy of Educational Sciences of Ukraine, Kyiv; The Graduate School for Social Research, Institute of Philosophy and Sociology of the Polish Academy of Sciences,Warsaw, PolandPalladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, UkraineFor many decades, scientists have tried to unravel the mysteries of the nervous system – the complex phenomenon that receives messages, processes information, and sends signals to the rest of the body. The most important scientific discoveries of the 19th and the 20th centuries paved the way for the 2000 Nobel Prize in Physiology or Medicine awarded to Arvid Carlsson, Paul Greengard and Eric Kandel “for their discoveries concerning signal transduction in the nervous system”. So, the beginning of the new millennium was “marked” by pioneering research into the chemical transmission of signals in the central nervous system, which created the foundation for a deeper understanding of the mediatory role of dopamine, the processes of slow synaptic transmission, short-term and long-term memory, and the mechanisms of action of antipsychotic and antidepressant drugs. The paper aims to outline the main stages of scientific activities of a Swedish neuropharmacologist Per Arvid Emil Carlsson and the American neurobiologists Paul Greengard and Eric Richard Kandel.http://ukrbiochemjournal.org/wp-content/uploads/2023/06/Danylova_TV_95_2.pdfarvid carlssonbraindopamineeric kandellearningmemorynervous systempaul greengardslow synaptic transmissionthe 2000 nobel prize in physiology or medicine |
| spellingShingle | T. V. Danylova S. V. Komisarenko Nobel prize winners Arvid Carlsson, Paul Greengard and Eric Kandel: the research of signal transduction in the nervous system The Ukrainian Biochemical Journal arvid carlsson brain dopamine eric kandel learning memory nervous system paul greengard slow synaptic transmission the 2000 nobel prize in physiology or medicine |
| title | Nobel prize winners Arvid Carlsson, Paul Greengard and Eric Kandel: the research of signal transduction in the nervous system |
| title_full | Nobel prize winners Arvid Carlsson, Paul Greengard and Eric Kandel: the research of signal transduction in the nervous system |
| title_fullStr | Nobel prize winners Arvid Carlsson, Paul Greengard and Eric Kandel: the research of signal transduction in the nervous system |
| title_full_unstemmed | Nobel prize winners Arvid Carlsson, Paul Greengard and Eric Kandel: the research of signal transduction in the nervous system |
| title_short | Nobel prize winners Arvid Carlsson, Paul Greengard and Eric Kandel: the research of signal transduction in the nervous system |
| title_sort | nobel prize winners arvid carlsson paul greengard and eric kandel the research of signal transduction in the nervous system |
| topic | arvid carlsson brain dopamine eric kandel learning memory nervous system paul greengard slow synaptic transmission the 2000 nobel prize in physiology or medicine |
| url | http://ukrbiochemjournal.org/wp-content/uploads/2023/06/Danylova_TV_95_2.pdf |
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