Comparative Study of Two Oxidizing Agents, Chloramine T and Iodo-Gen<sup>®</sup>, for the Radiolabeling of β-CIT with Iodine-131: Relevance for Parkinson’s Disease

Comparative Study of Two Oxidizing Agents, Chloramine T and Iodo-Gen<sup>®</sup>, for the Radiolabeling of β-CIT with Iodine-131: Relevance for Parkinson’s Disease

Parkinson&#8217;s disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the <i>substantia nigra pars compacta</i>, leading to alteration of the integrity of dopaminergic transporters (DATs). In recent years, some radiopharmaceuticals have be...

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Bibliographic Details
Main Authors: Ana Claudia R. Durante, Danielle V. Sobral, Ana Claudia C. Miranda, Érika V. de Almeida, Leonardo L. Fuscaldi, Marycel R. F. F. de Barboza, Luciana Malavolta
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Pharmaceuticals
Subjects:
Chloramine T
electrophilic radioiodination
iodine-131
Iodo-Gen<sup>®</sup>
oxidizing agent
β-CIT.
Online Access:https://www.mdpi.com/1424-8247/12/1/25

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