The influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562)
Cell culture K562 samples were treated with fullerenol (C6o(OH)24) at a concentration of 10 nmol/mL and thereafter irradiated with X-rays (24Gy). The activity of gamma-glutamyltransfrease (γ-GT), total superoxide-dismutase (SOD) and glutathion-peroxidase (GSH-Px) was determined 1, 24 and 48 hours af...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Association of Chemical Engineers of Serbia
2007-01-01
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| Series: | Hemijska Industrija |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0367-598X/2007/0367-598X0703164B.pdf |
| _version_ | 1818766390679568384 |
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| author | Bogdanović Višnja Stankov Karmen Nikolić Aleksandra Ičević Ivana Šolajić Slavica Bogdanović Gordana Đorđević Aleksandar |
| author_facet | Bogdanović Višnja Stankov Karmen Nikolić Aleksandra Ičević Ivana Šolajić Slavica Bogdanović Gordana Đorđević Aleksandar |
| author_sort | Bogdanović Višnja |
| collection | DOAJ |
| description | Cell culture K562 samples were treated with fullerenol (C6o(OH)24) at a concentration of 10 nmol/mL and thereafter irradiated with X-rays (24Gy). The activity of gamma-glutamyltransfrease (γ-GT), total superoxide-dismutase (SOD) and glutathion-peroxidase (GSH-Px) was determined 1, 24 and 48 hours after irradiation. Irradiation induces an increase in the activity of all the investigated enzymes. Fullerenol in the applied dose decreased the γ-GT activity 24 and 48 h after irradiation. The total SOD activity is increased in both pretreated groups except in the iradiated group at the 48th hour. Treatment with fullerenol before irradiation increased GSH-Px activity in irradiated groups and decreased it in the control groups. |
| first_indexed | 2024-12-18T08:33:14Z |
| format | Article |
| id | doaj.art-83218219023646f2be1aafda60950462 |
| institution | Directory Open Access Journal |
| issn | 0367-598X |
| language | English |
| last_indexed | 2024-12-18T08:33:14Z |
| publishDate | 2007-01-01 |
| publisher | Association of Chemical Engineers of Serbia |
| record_format | Article |
| series | Hemijska Industrija |
| spelling | doaj.art-83218219023646f2be1aafda609504622022-12-21T21:14:25ZengAssociation of Chemical Engineers of SerbiaHemijska Industrija0367-598X2007-01-0161316416610.2298/HEMIND0703164BThe influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562)Bogdanović VišnjaStankov KarmenNikolić AleksandraIčević IvanaŠolajić SlavicaBogdanović GordanaĐorđević AleksandarCell culture K562 samples were treated with fullerenol (C6o(OH)24) at a concentration of 10 nmol/mL and thereafter irradiated with X-rays (24Gy). The activity of gamma-glutamyltransfrease (γ-GT), total superoxide-dismutase (SOD) and glutathion-peroxidase (GSH-Px) was determined 1, 24 and 48 hours after irradiation. Irradiation induces an increase in the activity of all the investigated enzymes. Fullerenol in the applied dose decreased the γ-GT activity 24 and 48 h after irradiation. The total SOD activity is increased in both pretreated groups except in the iradiated group at the 48th hour. Treatment with fullerenol before irradiation increased GSH-Px activity in irradiated groups and decreased it in the control groups.http://www.doiserbia.nb.rs/img/doi/0367-598X/2007/0367-598X0703164B.pdfX-irradiationCell cultureAntioxidative enzymes |
| spellingShingle | Bogdanović Višnja Stankov Karmen Nikolić Aleksandra Ičević Ivana Šolajić Slavica Bogdanović Gordana Đorđević Aleksandar The influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562) Hemijska Industrija X-irradiation Cell culture Antioxidative enzymes |
| title | The influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562) |
| title_full | The influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562) |
| title_fullStr | The influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562) |
| title_full_unstemmed | The influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562) |
| title_short | The influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562) |
| title_sort | influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line k562 |
| topic | X-irradiation Cell culture Antioxidative enzymes |
| url | http://www.doiserbia.nb.rs/img/doi/0367-598X/2007/0367-598X0703164B.pdf |
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