Central nervous system metastasis in epithelial ovarian carcinoma: a case report and literature review.
Objective:To report involvement of the central nervous system (CNS) following epithelial ovarian cancer is rare. Advances in management of ovarian cancer by use of primary surgery including abdominal hysterectomy, bilateral salpingo'oophorectomy should attain as complete a cytoreduction as poss...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2015-03-01
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| Series: | Journal of Family and Reproductive Health |
| Subjects: | |
| Online Access: | https://jfrh.tums.ac.ir/index.php/jfrh/article/view/207 |
| _version_ | 1818900781067141120 |
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| author | Fereshteh Fakour Hadi Hajizadeh Fallah Sina Khajeh Jahromi Parham Porteghali |
| author_facet | Fereshteh Fakour Hadi Hajizadeh Fallah Sina Khajeh Jahromi Parham Porteghali |
| author_sort | Fereshteh Fakour |
| collection | DOAJ |
| description | Objective:To report involvement of the central nervous system (CNS) following epithelial ovarian cancer is rare. Advances in management of ovarian cancer by use of primary surgery including abdominal hysterectomy, bilateral salpingo'oophorectomy should attain as complete a cytoreduction as possible and effective platinum-based chemotherapy have prolonged survival.
Case report:We present a case involving a 35-year-old Iranian woman diagnosed and treated for primary ovarian cancer in 2002. She underwent optimal cytoreductive surgery and chemotherapy treatment. Eight months after the initiation of therapy, multiple brain metastases without intraperitoneal lesions were found and treated with combination chemotherapy and whole brain radiotherapy (WBRT), without evidence of recurrent disease. The patient died from disease in December 2005.
Conclusion:In a patient suffering from neoplasm that rarely metastasizes to CNS, a careful clinical examination and proper therapeutic approach including chemotherapy may lead to prolong survival. |
| first_indexed | 2024-12-19T20:09:18Z |
| format | Article |
| id | doaj.art-8321f596b1ca424190671aa544cf8f1a |
| institution | Directory Open Access Journal |
| issn | 1735-8949 1735-9392 |
| language | English |
| last_indexed | 2024-12-19T20:09:18Z |
| publishDate | 2015-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Family and Reproductive Health |
| spelling | doaj.art-8321f596b1ca424190671aa544cf8f1a2022-12-21T20:07:21ZengTehran University of Medical SciencesJournal of Family and Reproductive Health1735-89491735-93922015-03-0191202Central nervous system metastasis in epithelial ovarian carcinoma: a case report and literature review.Fereshteh Fakour0Hadi Hajizadeh Fallah1Sina Khajeh Jahromi2Parham Porteghali3Reproductive Health Research Center, Guilan University of Medical Sciences, Rasht, Iran.Department of Pathology, Guilan University of Medical Sciences, Rasht, Iran.Reproductive Health Research Center, Guilan University of Medical Sciences, Rasht, Iran.Reproductive Health Research Center, Guilan University of Medical Sciences, Rasht, Iran.Objective:To report involvement of the central nervous system (CNS) following epithelial ovarian cancer is rare. Advances in management of ovarian cancer by use of primary surgery including abdominal hysterectomy, bilateral salpingo'oophorectomy should attain as complete a cytoreduction as possible and effective platinum-based chemotherapy have prolonged survival. Case report:We present a case involving a 35-year-old Iranian woman diagnosed and treated for primary ovarian cancer in 2002. She underwent optimal cytoreductive surgery and chemotherapy treatment. Eight months after the initiation of therapy, multiple brain metastases without intraperitoneal lesions were found and treated with combination chemotherapy and whole brain radiotherapy (WBRT), without evidence of recurrent disease. The patient died from disease in December 2005. Conclusion:In a patient suffering from neoplasm that rarely metastasizes to CNS, a careful clinical examination and proper therapeutic approach including chemotherapy may lead to prolong survival.https://jfrh.tums.ac.ir/index.php/jfrh/article/view/207Brain MetastasisChemotherapyOvarian Cancer |
| spellingShingle | Fereshteh Fakour Hadi Hajizadeh Fallah Sina Khajeh Jahromi Parham Porteghali Central nervous system metastasis in epithelial ovarian carcinoma: a case report and literature review. Journal of Family and Reproductive Health Brain Metastasis Chemotherapy Ovarian Cancer |
| title | Central nervous system metastasis in epithelial ovarian carcinoma: a case report and literature review. |
| title_full | Central nervous system metastasis in epithelial ovarian carcinoma: a case report and literature review. |
| title_fullStr | Central nervous system metastasis in epithelial ovarian carcinoma: a case report and literature review. |
| title_full_unstemmed | Central nervous system metastasis in epithelial ovarian carcinoma: a case report and literature review. |
| title_short | Central nervous system metastasis in epithelial ovarian carcinoma: a case report and literature review. |
| title_sort | central nervous system metastasis in epithelial ovarian carcinoma a case report and literature review |
| topic | Brain Metastasis Chemotherapy Ovarian Cancer |
| url | https://jfrh.tums.ac.ir/index.php/jfrh/article/view/207 |
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