Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trial
Background: There has been a steady increase in outpatient-based ultra-short duration gynecology surgeries. However, there are no detailed studies on anesthesia regimens for these surgeries. The aim of this study was to compare the effects of low-dose rocuronium and fentanyl single bolus for their s...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2022-04-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/49/4/10.31083/j.ceog4904098 |
| _version_ | 1811247767162454016 |
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| author | Eun-Su Choi Kuen Su Lee Da Som Kang Yoon Ji Choi Too Jae Min Yoon Sook Lee Jae Hwan Kim Kyung-Jin Min Woon Young Kim |
| author_facet | Eun-Su Choi Kuen Su Lee Da Som Kang Yoon Ji Choi Too Jae Min Yoon Sook Lee Jae Hwan Kim Kyung-Jin Min Woon Young Kim |
| author_sort | Eun-Su Choi |
| collection | DOAJ |
| description | Background: There has been a steady increase in outpatient-based ultra-short duration gynecology surgeries. However, there are no detailed studies on anesthesia regimens for these surgeries. The aim of this study was to compare the effects of low-dose rocuronium and fentanyl single bolus for their suitability with these patients. Methods: A total of 60 patients were randomly divided into three groups: a control group (group C, n = 20) that received 3 mL of normal saline; a fentanyl group (group F, n = 19) that received 1 mcg/kg of fentanyl; and a low-dose rocuronium group (group R, n = 20) that received 0.3 mg/kg of rocuronium. We collected hemodynamic data during anesthetic induction and the intraoperative period. We also investigated supraglottic airway (SGA) insertion condition, patient’s gross movements, and surgeon’s satisfaction. In addition, we evaluated the incidence of postoperative nausea and vomiting, pruritus, first voiding time and discharge time from the postanesthetic care unit. Results: Systolic, diastolic, and mean blood pressure were significantly lower in group F after SGA insertion (p = 0.031, p = 0.046 and p = 0.048). SGA insertion conditions scores were significantly worse in group C than in group F and group R for total score (p < 0.001). Also, the number of patient movements during surgery and the number of rescue fentanyl injections were significantly higher in group C than group F and group R (p = 0.005 and p < 0.001). Conclusion: Fentanyl administration at 1 mcg/kg has advantages compared with rocuronium and is a more suitable single agent regimen for outpatient-based ultra-short duration gynecology surgeries. |
| first_indexed | 2024-04-12T15:15:24Z |
| format | Article |
| id | doaj.art-832c2858dc29438e87b540c8b78426e4 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-04-12T15:15:24Z |
| publishDate | 2022-04-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-832c2858dc29438e87b540c8b78426e42022-12-22T03:27:38ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632022-04-014949810.31083/j.ceog4904098S0390-6663(22)01752-3Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trialEun-Su Choi0Kuen Su Lee1Da Som Kang2Yoon Ji Choi3Too Jae Min4Yoon Sook Lee5Jae Hwan Kim6Kyung-Jin Min7Woon Young Kim8Department of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, 15355 Gyeonggi-do, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Uijeongbu Eulji Medical Center, Eulji University, 15355 Gyeonggi-do, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, 15355 Gyeonggi-do, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, 15355 Gyeonggi-do, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, 15355 Gyeonggi-do, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, 15355 Gyeonggi-do, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, 15355 Gyeonggi-do, Republic of KoreaDepartment of Obstetrics and Gynecology, Korea University Ansan Hospital, 15355 Gyeonggi-do, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, 15355 Gyeonggi-do, Republic of KoreaBackground: There has been a steady increase in outpatient-based ultra-short duration gynecology surgeries. However, there are no detailed studies on anesthesia regimens for these surgeries. The aim of this study was to compare the effects of low-dose rocuronium and fentanyl single bolus for their suitability with these patients. Methods: A total of 60 patients were randomly divided into three groups: a control group (group C, n = 20) that received 3 mL of normal saline; a fentanyl group (group F, n = 19) that received 1 mcg/kg of fentanyl; and a low-dose rocuronium group (group R, n = 20) that received 0.3 mg/kg of rocuronium. We collected hemodynamic data during anesthetic induction and the intraoperative period. We also investigated supraglottic airway (SGA) insertion condition, patient’s gross movements, and surgeon’s satisfaction. In addition, we evaluated the incidence of postoperative nausea and vomiting, pruritus, first voiding time and discharge time from the postanesthetic care unit. Results: Systolic, diastolic, and mean blood pressure were significantly lower in group F after SGA insertion (p = 0.031, p = 0.046 and p = 0.048). SGA insertion conditions scores were significantly worse in group C than in group F and group R for total score (p < 0.001). Also, the number of patient movements during surgery and the number of rescue fentanyl injections were significantly higher in group C than group F and group R (p = 0.005 and p < 0.001). Conclusion: Fentanyl administration at 1 mcg/kg has advantages compared with rocuronium and is a more suitable single agent regimen for outpatient-based ultra-short duration gynecology surgeries.https://www.imrpress.com/journal/CEOG/49/4/10.31083/j.ceog4904098ambulatory anesthesiafentanylgynecology surgeryrocuronium |
| spellingShingle | Eun-Su Choi Kuen Su Lee Da Som Kang Yoon Ji Choi Too Jae Min Yoon Sook Lee Jae Hwan Kim Kyung-Jin Min Woon Young Kim Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trial Clinical and Experimental Obstetrics & Gynecology ambulatory anesthesia fentanyl gynecology surgery rocuronium |
| title | Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trial |
| title_full | Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trial |
| title_fullStr | Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trial |
| title_full_unstemmed | Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trial |
| title_short | Comparison between use of fentanyl and rocuronium on outpatient undergoing ultra-short duration gynecologic surgery: a randomized, double-blind, controlled trial |
| title_sort | comparison between use of fentanyl and rocuronium on outpatient undergoing ultra short duration gynecologic surgery a randomized double blind controlled trial |
| topic | ambulatory anesthesia fentanyl gynecology surgery rocuronium |
| url | https://www.imrpress.com/journal/CEOG/49/4/10.31083/j.ceog4904098 |
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