SMAC Mimetic BV6 Co-Treatment Downregulates the Factors Involved in Resistance and Relapse of Cancer: IAPs and Autophagy

SMAC Mimetic BV6 Co-Treatment Downregulates the Factors Involved in Resistance and Relapse of Cancer: IAPs and Autophagy

Cancer is the utmost common disease-causing death worldwide, characterized by uncontrollable cell division with the potential of metastasis. Overexpression of the Inhibitors of Apoptosis proteins (IAPs) and autophagy correlates with tumorigenesis, therapeutic resistance, and reoccurrence after antic...

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Bibliographic Details
Main Authors: Sahar Rafat, Prabhakar Singh, Kamlesh Kumar Pandey, Saleh A. Almatroodi, Mohammed A. Alsahli, Ahmad Almatroudi, Arshad Husain Rahmani, Kapil Dev
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biology
Subjects:
autophagy
apoptosis
IAPs
smac mimetics
breast cancer
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Online Access:https://www.mdpi.com/2079-7737/11/11/1581

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