Breast cancer, psychological distress and life events among young women

<p>Abstract</p> <p>Since 1983, studies have suggested an interaction between the severe life events, psychological distress and the etiology of Cancer. However, these associations are still under dispute.</p> <p><b><it>The aim </it></b>of the pre...

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Main Authors: Shoham-Vardi Ilana, Siboni-Samocha Orly, Carmil Devora, Peled Ronit
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/245
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author Shoham-Vardi Ilana
Siboni-Samocha Orly
Carmil Devora
Peled Ronit
author_facet Shoham-Vardi Ilana
Siboni-Samocha Orly
Carmil Devora
Peled Ronit
author_sort Shoham-Vardi Ilana
collection DOAJ
description <p>Abstract</p> <p>Since 1983, studies have suggested an interaction between the severe life events, psychological distress and the etiology of Cancer. However, these associations are still under dispute.</p> <p><b><it>The aim </it></b>of the present study was to examine the relationship between life events, psychological distress and Breast Cancer (BC) among young women.</p> <p>Methods</p> <p>A case control study. The study population included 622 women, under the age of 45 years. 255 were diagnosed for BC, and 367 were healthy women. A validated Brief Symptom Inventory (BSI) and Life Event Questionnaire were used.</p> <p>Results</p> <p>The cases presented significantly higher scores of depression compared to the controls and significant lower scores of happiness and optimism. A significant difference was found when comparing the groups according to the cumulative number of life events (two or more events). A multivariate analysis suggest that exposure to more than one life event is positively associated with BC [Odds Ratio(OR) :1.62 95% Confidence Interval (CI): 1.09–2.40], and that a general feeling of happiness and optimism has a "protective effect" on the etiology of BC. (OR-0.75, 95% CI:0.64–0.86).</p> <p>Conclusion</p> <p>Young women who were exposed to a number of life events, should be considered as a risk group for BC and treated accordingly.</p>
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spelling doaj.art-832e46e8ae834ace98d582df741a5b922022-12-22T03:06:14ZengBMCBMC Cancer1471-24072008-08-018124510.1186/1471-2407-8-245Breast cancer, psychological distress and life events among young womenShoham-Vardi IlanaSiboni-Samocha OrlyCarmil DevoraPeled Ronit<p>Abstract</p> <p>Since 1983, studies have suggested an interaction between the severe life events, psychological distress and the etiology of Cancer. However, these associations are still under dispute.</p> <p><b><it>The aim </it></b>of the present study was to examine the relationship between life events, psychological distress and Breast Cancer (BC) among young women.</p> <p>Methods</p> <p>A case control study. The study population included 622 women, under the age of 45 years. 255 were diagnosed for BC, and 367 were healthy women. A validated Brief Symptom Inventory (BSI) and Life Event Questionnaire were used.</p> <p>Results</p> <p>The cases presented significantly higher scores of depression compared to the controls and significant lower scores of happiness and optimism. A significant difference was found when comparing the groups according to the cumulative number of life events (two or more events). A multivariate analysis suggest that exposure to more than one life event is positively associated with BC [Odds Ratio(OR) :1.62 95% Confidence Interval (CI): 1.09–2.40], and that a general feeling of happiness and optimism has a "protective effect" on the etiology of BC. (OR-0.75, 95% CI:0.64–0.86).</p> <p>Conclusion</p> <p>Young women who were exposed to a number of life events, should be considered as a risk group for BC and treated accordingly.</p>http://www.biomedcentral.com/1471-2407/8/245
spellingShingle Shoham-Vardi Ilana
Siboni-Samocha Orly
Carmil Devora
Peled Ronit
Breast cancer, psychological distress and life events among young women
BMC Cancer
title Breast cancer, psychological distress and life events among young women
title_full Breast cancer, psychological distress and life events among young women
title_fullStr Breast cancer, psychological distress and life events among young women
title_full_unstemmed Breast cancer, psychological distress and life events among young women
title_short Breast cancer, psychological distress and life events among young women
title_sort breast cancer psychological distress and life events among young women
url http://www.biomedcentral.com/1471-2407/8/245
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AT sibonisamochaorly breastcancerpsychologicaldistressandlifeeventsamongyoungwomen
AT carmildevora breastcancerpsychologicaldistressandlifeeventsamongyoungwomen
AT peledronit breastcancerpsychologicaldistressandlifeeventsamongyoungwomen