Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours

<p>Abstract</p> <p>Esophageal perforation is a rare and potentially life-threatening condition. Early clinical suspicion and imaging is important for case management to achieve a good outcome. However, recent studies continue to report high morbidity and mortality greater than 20%...

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Main Authors: Søreide Jon, Viste Asgaut
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Subjects:
Online Access:http://www.sjtrem.com/content/19/1/66
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author Søreide Jon
Viste Asgaut
author_facet Søreide Jon
Viste Asgaut
author_sort Søreide Jon
collection DOAJ
description <p>Abstract</p> <p>Esophageal perforation is a rare and potentially life-threatening condition. Early clinical suspicion and imaging is important for case management to achieve a good outcome. However, recent studies continue to report high morbidity and mortality greater than 20% from esophageal perforation. At least half of the perforations are iatrogenic, mostly related to endoscopic instrumentation used in the upper gastrointestinal tract, while about a third are spontaneous perforations. Surgical treatment remains an important option for many patients, but a non-operative approach, with or without use of an endoscopic stent or placement of internal or external drains, should be considered when the clinical situation allows for a less invasive approach. The rarity of this emergency makes it difficult for a physician to obtain extensive individual clinical experience; it is also challenging to obtain firm scientific evidence that informs patient management and clinical decision-making. Improved attention to non-specific symptoms and signs and early diagnosis based on imaging may translate into better outcomes for this group of patients, many of whom are elderly with significant comorbidity.</p>
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spelling doaj.art-8330bc1d55c5491eab21e2f40db2e9552022-12-22T01:17:21ZengBMCScandinavian Journal of Trauma, Resuscitation and Emergency Medicine1757-72412011-10-011916610.1186/1757-7241-19-66Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hoursSøreide JonViste Asgaut<p>Abstract</p> <p>Esophageal perforation is a rare and potentially life-threatening condition. Early clinical suspicion and imaging is important for case management to achieve a good outcome. However, recent studies continue to report high morbidity and mortality greater than 20% from esophageal perforation. At least half of the perforations are iatrogenic, mostly related to endoscopic instrumentation used in the upper gastrointestinal tract, while about a third are spontaneous perforations. Surgical treatment remains an important option for many patients, but a non-operative approach, with or without use of an endoscopic stent or placement of internal or external drains, should be considered when the clinical situation allows for a less invasive approach. The rarity of this emergency makes it difficult for a physician to obtain extensive individual clinical experience; it is also challenging to obtain firm scientific evidence that informs patient management and clinical decision-making. Improved attention to non-specific symptoms and signs and early diagnosis based on imaging may translate into better outcomes for this group of patients, many of whom are elderly with significant comorbidity.</p>http://www.sjtrem.com/content/19/1/66Esophagusperforationearly diagnosissurgerynon-surgical managementendoscopy
spellingShingle Søreide Jon
Viste Asgaut
Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Esophagus
perforation
early diagnosis
surgery
non-surgical management
endoscopy
title Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours
title_full Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours
title_fullStr Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours
title_full_unstemmed Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours
title_short Esophageal perforation: diagnostic work-up and clinical decision-making in the first 24 hours
title_sort esophageal perforation diagnostic work up and clinical decision making in the first 24 hours
topic Esophagus
perforation
early diagnosis
surgery
non-surgical management
endoscopy
url http://www.sjtrem.com/content/19/1/66
work_keys_str_mv AT søreidejon esophagealperforationdiagnosticworkupandclinicaldecisionmakinginthefirst24hours
AT visteasgaut esophagealperforationdiagnosticworkupandclinicaldecisionmakinginthefirst24hours