Influence of the Probiotic <i>L. reuteri</i> on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic Review
The aim of this systematic review was to evaluate the actual efficacy of <i>Lactobacillus reuteri</i> (<i>L. reuteri</i>) on the periodontal clinical parameters when used concomitantly to the nonsurgical periodontal treatment. Searches were conducted through PubMed Central, O...
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| Format: | Article |
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MDPI AG
2023-05-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/11/6/1449 |
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| author | Carlota Ochôa Filipe Castro José Frias Bulhosa Conceição Manso Juliana Campos Hasse Fernandes Gustavo Vicentis Oliveira Fernandes |
| author_facet | Carlota Ochôa Filipe Castro José Frias Bulhosa Conceição Manso Juliana Campos Hasse Fernandes Gustavo Vicentis Oliveira Fernandes |
| author_sort | Carlota Ochôa |
| collection | DOAJ |
| description | The aim of this systematic review was to evaluate the actual efficacy of <i>Lactobacillus reuteri</i> (<i>L. reuteri</i>) on the periodontal clinical parameters when used concomitantly to the nonsurgical periodontal treatment. Searches were conducted through PubMed Central, Online Knowledge Library, Science Direct, Scielo, and Cochrane databases from 2012 to 2022. The focused question was “In patients with periodontitis, will the probiotic <i>L. reuteri</i>, when administrated as an adjunct to nonsurgical periodontal treatment, compared to the nonsurgical periodontal treatment alone, result in better clinical outcomes?” The following information was extracted from the articles: author and year of publication, type of study, follow-up, sample size and number of defects, and clinical characteristics and details. All included studies were qualitatively assessed using the Critical Appraisal tools according to the Joanna Briggs Institute. Twenty-four articles were full-text reading, but only 9 articles were included. The number of patients enrolled was 287, aged between 18 and 56 years. All periodontal parameters were evaluated. The “follow-up” varied (14, 40, 84, 90, 180, and 360 days). Most articles supported the clinical benefits of <i>L. reuteri</i> as an adjunct to SRP compared to SRP alone. A common finding at the beginning period was thatno statistically different results were observed between the test and control groups; otherwise, at the last period, a significant improvement was found in favor of the probiotic use (<i>p</i> = 0.001) for all the clinical parameters. The use of <i>L. reuteri</i> as an adjunct to nonsurgical periodontal treatment may result in significantly better clinical outcomes than nonsurgical periodontal treatment alone; but the conclusion must be carefully interpreted because of the heterogeneity found among the studies. |
| first_indexed | 2024-03-11T02:08:22Z |
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| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-11T02:08:22Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-8337bb2e7bb34fe4878fd69028be350f2023-11-18T11:42:03ZengMDPI AGMicroorganisms2076-26072023-05-01116144910.3390/microorganisms11061449Influence of the Probiotic <i>L. reuteri</i> on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic ReviewCarlota Ochôa0Filipe Castro1José Frias Bulhosa2Conceição Manso3Juliana Campos Hasse Fernandes4Gustavo Vicentis Oliveira Fernandes5FP-I3ID, FCS, Fernando Pessoa University, 4249-004 Porto, PortugalFP-I3ID, FCS, Fernando Pessoa University, 4249-004 Porto, PortugalFP-I3ID, FCS, Fernando Pessoa University, 4249-004 Porto, PortugalFP-I3ID, FCS, Fernando Pessoa University, 4249-004 Porto, PortugalPeriodontics and Oral Medicine Department, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USAPeriodontics and Oral Medicine Department, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USAThe aim of this systematic review was to evaluate the actual efficacy of <i>Lactobacillus reuteri</i> (<i>L. reuteri</i>) on the periodontal clinical parameters when used concomitantly to the nonsurgical periodontal treatment. Searches were conducted through PubMed Central, Online Knowledge Library, Science Direct, Scielo, and Cochrane databases from 2012 to 2022. The focused question was “In patients with periodontitis, will the probiotic <i>L. reuteri</i>, when administrated as an adjunct to nonsurgical periodontal treatment, compared to the nonsurgical periodontal treatment alone, result in better clinical outcomes?” The following information was extracted from the articles: author and year of publication, type of study, follow-up, sample size and number of defects, and clinical characteristics and details. All included studies were qualitatively assessed using the Critical Appraisal tools according to the Joanna Briggs Institute. Twenty-four articles were full-text reading, but only 9 articles were included. The number of patients enrolled was 287, aged between 18 and 56 years. All periodontal parameters were evaluated. The “follow-up” varied (14, 40, 84, 90, 180, and 360 days). Most articles supported the clinical benefits of <i>L. reuteri</i> as an adjunct to SRP compared to SRP alone. A common finding at the beginning period was thatno statistically different results were observed between the test and control groups; otherwise, at the last period, a significant improvement was found in favor of the probiotic use (<i>p</i> = 0.001) for all the clinical parameters. The use of <i>L. reuteri</i> as an adjunct to nonsurgical periodontal treatment may result in significantly better clinical outcomes than nonsurgical periodontal treatment alone; but the conclusion must be carefully interpreted because of the heterogeneity found among the studies.https://www.mdpi.com/2076-2607/11/6/1449periodontal diseaseprobioticsnonsurgical treatment<i>L. reuteri</i> |
| spellingShingle | Carlota Ochôa Filipe Castro José Frias Bulhosa Conceição Manso Juliana Campos Hasse Fernandes Gustavo Vicentis Oliveira Fernandes Influence of the Probiotic <i>L. reuteri</i> on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic Review Microorganisms periodontal disease probiotics nonsurgical treatment <i>L. reuteri</i> |
| title | Influence of the Probiotic <i>L. reuteri</i> on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic Review |
| title_full | Influence of the Probiotic <i>L. reuteri</i> on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic Review |
| title_fullStr | Influence of the Probiotic <i>L. reuteri</i> on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic Review |
| title_full_unstemmed | Influence of the Probiotic <i>L. reuteri</i> on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic Review |
| title_short | Influence of the Probiotic <i>L. reuteri</i> on Periodontal Clinical Parameters after Nonsurgical Treatment: A Systematic Review |
| title_sort | influence of the probiotic i l reuteri i on periodontal clinical parameters after nonsurgical treatment a systematic review |
| topic | periodontal disease probiotics nonsurgical treatment <i>L. reuteri</i> |
| url | https://www.mdpi.com/2076-2607/11/6/1449 |
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