Acute Disseminated Encephalomyelitis: A Rare Complication of Varicella Zoster Infection in an Adult

Acute Disseminated Encephalomyelitis (ADEM) is a mutifocal, demyelinating disease of the brain and spinal cord of acute onset. It usually occurs after viral infections or post vaccination. Its occurrence in immunocompetent middle-aged adults, that too without cerebral dysfunction following Varicella...

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Bibliographic Details
Main Authors: Jahnvi Dhar, Lokesh Kumar, Pranav Ish, S Anuradha
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2018-02-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/11194/32208_F(AP)_PF1(AD_AP)_PFA(MJ_SL).pdf
Description
Summary:Acute Disseminated Encephalomyelitis (ADEM) is a mutifocal, demyelinating disease of the brain and spinal cord of acute onset. It usually occurs after viral infections or post vaccination. Its occurrence in immunocompetent middle-aged adults, that too without cerebral dysfunction following Varicella Zoster Virus (VZV) infection is extremely rare. Here, we report a case of a 42-year-old female who developed ADEM after an episode of VZV infection. The patient responded dramatically to corticosteroids and made complete neurological recovery. Though she had extensive lesions on her brain MRI, she had no symptoms/signs related to brain involvement clinically. To the best of our knowledge, such a presentation has not been reported in literature so far.
ISSN:2249-782X
0973-709X