The Golden Age: Shining the Light on Theragnostics
Gold nanoparticles have attracted unprecedented attention as one of the leading nanomaterials in the field of biomedicine. Of particular interest are their inherent and geometrically tunable optical properties upon the interaction with light, facilitating breakthroughs in light‐mediated diagnosis an...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2021-08-01
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| Series: | Advanced NanoBiomed Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/anbr.202000103 |
| _version_ | 1818355613899423744 |
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| author | Yamin Yang Hongjun Wang |
| author_facet | Yamin Yang Hongjun Wang |
| author_sort | Yamin Yang |
| collection | DOAJ |
| description | Gold nanoparticles have attracted unprecedented attention as one of the leading nanomaterials in the field of biomedicine. Of particular interest are their inherent and geometrically tunable optical properties upon the interaction with light, facilitating breakthroughs in light‐mediated diagnosis and therapeutics. Herein, an up‐to‐date overview of the current research in utilizing versatile gold‐based nanosystems with distinctive optical features for optical imaging and phototherapy is provided. The recent advances in optical biosensing, surface‐enhanced Raman scattering‐based detection, photoacoustic imaging, optical coherence tomography, photothermal therapy, light‐triggered drug release, photodynamic therapy, and optomodulation of neural functions using the novel and elegant gold nanostructures of unique design are summarized. In recognition of the burgeoning popularity of integrating multiple diagnostic and therapeutic functions in one system, recent developments of various multifunctional gold nanoplatforms for the light‐enabled concomitant diagnosis and therapy are also highlighted. In the end, the current limitations and perspectives in clinical translation of gold nanomaterial‐assisted photodiagnosis and phototherapy are discussed along with the concluding remarks. |
| first_indexed | 2024-12-13T19:44:07Z |
| format | Article |
| id | doaj.art-833b8df15593468fbedd90ecd95c71ed |
| institution | Directory Open Access Journal |
| issn | 2699-9307 |
| language | English |
| last_indexed | 2024-12-13T19:44:07Z |
| publishDate | 2021-08-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Advanced NanoBiomed Research |
| spelling | doaj.art-833b8df15593468fbedd90ecd95c71ed2022-12-21T23:33:37ZengWiley-VCHAdvanced NanoBiomed Research2699-93072021-08-0118n/an/a10.1002/anbr.202000103The Golden Age: Shining the Light on TheragnosticsYamin Yang0Hongjun Wang1Department of Biomedical Engineering Nanjing University of Aeronautics and Astronautics Nanjing Jiangsu 211106 ChinaDepartment of Biomedical Engineering Stevens Institute of Technology Hoboken NJ 07030 USAGold nanoparticles have attracted unprecedented attention as one of the leading nanomaterials in the field of biomedicine. Of particular interest are their inherent and geometrically tunable optical properties upon the interaction with light, facilitating breakthroughs in light‐mediated diagnosis and therapeutics. Herein, an up‐to‐date overview of the current research in utilizing versatile gold‐based nanosystems with distinctive optical features for optical imaging and phototherapy is provided. The recent advances in optical biosensing, surface‐enhanced Raman scattering‐based detection, photoacoustic imaging, optical coherence tomography, photothermal therapy, light‐triggered drug release, photodynamic therapy, and optomodulation of neural functions using the novel and elegant gold nanostructures of unique design are summarized. In recognition of the burgeoning popularity of integrating multiple diagnostic and therapeutic functions in one system, recent developments of various multifunctional gold nanoplatforms for the light‐enabled concomitant diagnosis and therapy are also highlighted. In the end, the current limitations and perspectives in clinical translation of gold nanomaterial‐assisted photodiagnosis and phototherapy are discussed along with the concluding remarks.https://doi.org/10.1002/anbr.202000103gold nanoparticlesphotoacoustic imagingphotodynamic therapyphotothermal therapysurface plasmon resonances |
| spellingShingle | Yamin Yang Hongjun Wang The Golden Age: Shining the Light on Theragnostics Advanced NanoBiomed Research gold nanoparticles photoacoustic imaging photodynamic therapy photothermal therapy surface plasmon resonances |
| title | The Golden Age: Shining the Light on Theragnostics |
| title_full | The Golden Age: Shining the Light on Theragnostics |
| title_fullStr | The Golden Age: Shining the Light on Theragnostics |
| title_full_unstemmed | The Golden Age: Shining the Light on Theragnostics |
| title_short | The Golden Age: Shining the Light on Theragnostics |
| title_sort | golden age shining the light on theragnostics |
| topic | gold nanoparticles photoacoustic imaging photodynamic therapy photothermal therapy surface plasmon resonances |
| url | https://doi.org/10.1002/anbr.202000103 |
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