ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials

ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials

The profiling and monitoring of immune responses are key elements in the evaluation of the efficacy and development of new biotherapies, and a number of assays have been introduced for analyzing various immune parameters before, during, and after immunotherapy. The choice of immune assays for a give...

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Bibliographic Details
Main Authors: Thomas J. Sayers, Michael R. Shurin, Kimberly Dunham, Susan Strobl, Anatoli M. Malyguine
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Cells
Subjects:
ELISPOT
cancer clinical trial
IFN-g
Granzyme B
Perforin
cytotoxicity
T cell
Online Access:http://www.mdpi.com/2073-4409/1/2/111

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