Scalable Generation of Pre‐Vascularized and Functional Human Beige Adipose Organoids

Scalable Generation of Pre‐Vascularized and Functional Human Beige Adipose Organoids

Abstract Obesity and type 2 diabetes are becoming a global sociobiomedical burden. Beige adipocytes are emerging as key inducible actors and putative relevant therapeutic targets for improving metabolic health. However, in vitro models of human beige adipose tissue are currently lacking and hinder r...

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Bibliographic Details
Main Authors: Mélanie Escudero, Laurence Vaysse, Gozde Eke, Marion Peyrou, Francesc Villarroya, Sophie Bonnel, Yannick Jeanson, Louisa Boyer, Christophe Vieu, Benoit Chaput, Xi Yao, Frédéric Deschaseaux, Mélissa Parny, Isabelle Raymond‐Letron, Christian Dani, Audrey Carrière, Laurent Malaquin, Louis Casteilla
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Advanced Science
Subjects:
adipose‐derived stroma/stem cells (ASC)
beige and brown adipocytes
guided‐assembly
hydrogels
microtissues
organoid morphogenesis
Online Access:https://doi.org/10.1002/advs.202301499

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