Dicephalus dipus dibrachius twins: report of an autopsy case

Dicephalus dipus dibrachius twins are a rare form of conjoined twins. An autopsy of conjoined dicephalus twins is reported. The diagnosis was performed during the pregnancy and the family received a judicial authorization for termination of pregnancy. The preterm newborn progressed to cardiac arrest...

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Main Authors: Cristiano Claudino Oliveira, Claudia Aparecida Rainho, Maria Aparecida Custódio Domingues
Format: Article
Language:English
Published: University of São Paulo 2014-06-01
Series:Autopsy and Case Reports
Subjects:
Online Access:http://www.revistas.usp.br/autopsy/article/view/82531
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author Cristiano Claudino Oliveira
Claudia Aparecida Rainho
Maria Aparecida Custódio Domingues
author_facet Cristiano Claudino Oliveira
Claudia Aparecida Rainho
Maria Aparecida Custódio Domingues
author_sort Cristiano Claudino Oliveira
collection DOAJ
description Dicephalus dipus dibrachius twins are a rare form of conjoined twins. An autopsy of conjoined dicephalus twins is reported. The diagnosis was performed during the pregnancy and the family received a judicial authorization for termination of pregnancy. The preterm newborn progressed to cardiac arrest and died following a court order to terminate the pregnancy. The conceptus presented two arms, two legs, a trunk, two heads, and a single umbilical cord. The two spinal columns presented vertebral fusion in the sacral region. The heart exhibited complex malformations. The external genitalia were female; and cytogenetic analysis confirmed female sex (46, XX). This analysis also corroborated the etiopathogenic hypotheses described for this abnormality, which proposes failures in embryonic formation rather than specific chromosomal alterations. Current identification of cases by ultrasound permits medical management and multidisciplinary action with the family, enabling the legal termination of pregnancy.
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spelling doaj.art-834a8599b4ee4bd3a1cd4cbd890568302022-12-22T01:05:38ZengUniversity of São PauloAutopsy and Case Reports2236-19602014-06-014210.4322/acr.%y.8253178353Dicephalus dipus dibrachius twins: report of an autopsy caseCristiano Claudino Oliveira0Claudia Aparecida Rainho1Maria Aparecida Custódio Domingues2Department of Pathology – Faculdade de Medicina de Botucatu – Universidade Estadual Paulista Júlio de Mesquita Filho – Botucatu/SPDepartment of Genetics – Instituto de Biociências – Universidade Estadual Paulista Júlio de Mesquita Filho – Botucatu/SPDepartment of Pathology – Faculdade de Medicina de Botucatu – Universidade Estadual Paulista Júlio de Mesquita Filho – Botucatu/SPDicephalus dipus dibrachius twins are a rare form of conjoined twins. An autopsy of conjoined dicephalus twins is reported. The diagnosis was performed during the pregnancy and the family received a judicial authorization for termination of pregnancy. The preterm newborn progressed to cardiac arrest and died following a court order to terminate the pregnancy. The conceptus presented two arms, two legs, a trunk, two heads, and a single umbilical cord. The two spinal columns presented vertebral fusion in the sacral region. The heart exhibited complex malformations. The external genitalia were female; and cytogenetic analysis confirmed female sex (46, XX). This analysis also corroborated the etiopathogenic hypotheses described for this abnormality, which proposes failures in embryonic formation rather than specific chromosomal alterations. Current identification of cases by ultrasound permits medical management and multidisciplinary action with the family, enabling the legal termination of pregnancy.http://www.revistas.usp.br/autopsy/article/view/82531AutopsyTwinsConjoinedCytogeneticsEmbryologyFetal Diseases
spellingShingle Cristiano Claudino Oliveira
Claudia Aparecida Rainho
Maria Aparecida Custódio Domingues
Dicephalus dipus dibrachius twins: report of an autopsy case
Autopsy and Case Reports
Autopsy
Twins
Conjoined
Cytogenetics
Embryology
Fetal Diseases
title Dicephalus dipus dibrachius twins: report of an autopsy case
title_full Dicephalus dipus dibrachius twins: report of an autopsy case
title_fullStr Dicephalus dipus dibrachius twins: report of an autopsy case
title_full_unstemmed Dicephalus dipus dibrachius twins: report of an autopsy case
title_short Dicephalus dipus dibrachius twins: report of an autopsy case
title_sort dicephalus dipus dibrachius twins report of an autopsy case
topic Autopsy
Twins
Conjoined
Cytogenetics
Embryology
Fetal Diseases
url http://www.revistas.usp.br/autopsy/article/view/82531
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