Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: Numerical study
This study reports a novel approach for early detection of malignant cancer cells in human organs using a birefringent photonic crystal fiber (PCF)-based optical sensor with dual demodulation. The PCF injects light into the middle hole, enhancing the radiated evanescent field. Analytes injected thro...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-07-01
|
| Series: | Results in Optics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666950123001451 |
| _version_ | 1797733837429538816 |
|---|---|
| author | Farhan Mumtaz |
| author_facet | Farhan Mumtaz |
| author_sort | Farhan Mumtaz |
| collection | DOAJ |
| description | This study reports a novel approach for early detection of malignant cancer cells in human organs using a birefringent photonic crystal fiber (PCF)-based optical sensor with dual demodulation. The PCF injects light into the middle hole, enhancing the radiated evanescent field. Analytes injected through the core cause a wavelength shift, measured by peak or dip shift. The proposed sensor has an optimal sensitivity of −7,940 nm/RIU, −8,265 nm/RIU, −9,747 nm/RIU, −9,006 nm/RIU, and −8,994 nm/RIU by peak shift and −8,745 nm/RIU, −10,728 nm/RIU, −8,721 nm/RIU, −10,113 nm/RIU, and −11,150 nm/RIU by dip shift for CRT-(Cervical tissue), BLD-(Blood), ADG-(Adrenal gland), BRT-(Breast) type-1 and type-2 cells, respectively. The PCF sensor presents a shorter sensing length of 550 µm. Results suggest the sensor is effective in detecting malignant neoplastic cells in earlier stages, making it a promising tool for cancer diagnosis and treatment. |
| first_indexed | 2024-03-12T12:35:21Z |
| format | Article |
| id | doaj.art-834cc2156f0f4b2d95262107652cdaa2 |
| institution | Directory Open Access Journal |
| issn | 2666-9501 |
| language | English |
| last_indexed | 2024-03-12T12:35:21Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Optics |
| spelling | doaj.art-834cc2156f0f4b2d95262107652cdaa22023-08-29T04:18:17ZengElsevierResults in Optics2666-95012023-07-0112100493Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: Numerical studyFarhan Mumtaz0Department of Electrical and Computer Engineering, Missouri University of Science and Technology, Rolla, MO 65409-0040, USAThis study reports a novel approach for early detection of malignant cancer cells in human organs using a birefringent photonic crystal fiber (PCF)-based optical sensor with dual demodulation. The PCF injects light into the middle hole, enhancing the radiated evanescent field. Analytes injected through the core cause a wavelength shift, measured by peak or dip shift. The proposed sensor has an optimal sensitivity of −7,940 nm/RIU, −8,265 nm/RIU, −9,747 nm/RIU, −9,006 nm/RIU, and −8,994 nm/RIU by peak shift and −8,745 nm/RIU, −10,728 nm/RIU, −8,721 nm/RIU, −10,113 nm/RIU, and −11,150 nm/RIU by dip shift for CRT-(Cervical tissue), BLD-(Blood), ADG-(Adrenal gland), BRT-(Breast) type-1 and type-2 cells, respectively. The PCF sensor presents a shorter sensing length of 550 µm. Results suggest the sensor is effective in detecting malignant neoplastic cells in earlier stages, making it a promising tool for cancer diagnosis and treatment.http://www.sciencedirect.com/science/article/pii/S2666950123001451Photonic crystal fiberMalignant cancerous cellsOptical sensorDual demodulation approach |
| spellingShingle | Farhan Mumtaz Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: Numerical study Results in Optics Photonic crystal fiber Malignant cancerous cells Optical sensor Dual demodulation approach |
| title | Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: Numerical study |
| title_full | Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: Numerical study |
| title_fullStr | Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: Numerical study |
| title_full_unstemmed | Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: Numerical study |
| title_short | Detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber: Numerical study |
| title_sort | detection of critical cancer cells in human organs using dual demodulation photonic crystal fiber numerical study |
| topic | Photonic crystal fiber Malignant cancerous cells Optical sensor Dual demodulation approach |
| url | http://www.sciencedirect.com/science/article/pii/S2666950123001451 |
| work_keys_str_mv | AT farhanmumtaz detectionofcriticalcancercellsinhumanorgansusingdualdemodulationphotoniccrystalfibernumericalstudy |