A perfusion bioreactor-based 3D model of the subarachnoid space based on a meningeal tissue construct

A perfusion bioreactor-based 3D model of the subarachnoid space based on a meningeal tissue construct

Abstract Background Altered flow of cerebrospinal fluid (CSF) within the subarachnoid space (SAS) is connected to brain, but also optic nerve degenerative diseases. To overcome the lack of suitable in vitro models that faithfully recapitulate the intricate three-dimensional architecture, complex cel...

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Bibliographic Details
Main Authors: Albert Neutzner, Laura Power, Markus Dürrenberger, Hendrik P. N. Scholl, Peter Meyer, Hanspeter E. Killer, David Wendt, Corina Kohler
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Fluids and Barriers of the CNS
Subjects:
Optic nerve
Subarachnoid space
Meningothelial cells
Bioreactor
Optic nerve compartment syndrome
Cerebrospinal fluid
Online Access:http://link.springer.com/article/10.1186/s12987-019-0137-6

Internet

http://link.springer.com/article/10.1186/s12987-019-0137-6

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