Genetic variants of CTLA4 are associated with clinical outcome of patients with multiple myeloma

Genetic variants of CTLA4 are associated with clinical outcome of patients with multiple myeloma

Immune dysfunction in patients with multiple myeloma (MM) affects both the innate and adaptive immune system. Molecules involved in the immune checkpoint pathways are essential to determine the ability of cancer cells to escape from the immune system surveillance. However, few data are available con...

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Bibliographic Details
Main Authors: Yolanda Gonzalez-Montes, Rocío Rodriguez-Romanos, Alicia Villavicencio, Gemma Osca-Gelis, Marta González-Bártulos, Francesca Llopis, Victòria Clapes, Albert Oriol, Anna Sureda, Lourdes Escoda, Josep Sarrà, Ana Garzó, Natàlia Lloveras, Isabel Díez, Isabel Granada, David Gallardo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
CTLA4 polymorphisms
multiple myeloma
immune checkpoint
bone marrow microenvironment
cytogenetics and molecular genetics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1158105/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1158105/full

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