Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model
Research objective was to compare effects of transplantation of cells and their nucleus on model alimentary dislipoproteinemia. Experiment is executed on the rabbits containing on an atherogenous diet. In blood serum of animals studied changes of a lipide exchange, in a liver — level of stresses-pro...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Siberian State Medical University (Tomsk)
2011-12-01
|
| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1496 |
| _version_ | 1827991728529866752 |
|---|---|
| author | Yu. I. Pivovarov T. Ye. Kurilskaya A. S. Sergeyeva I. V. Babushkina B. K. Baduyev G. B. Borovsky |
| author_facet | Yu. I. Pivovarov T. Ye. Kurilskaya A. S. Sergeyeva I. V. Babushkina B. K. Baduyev G. B. Borovsky |
| author_sort | Yu. I. Pivovarov |
| collection | DOAJ |
| description | Research objective was to compare effects of transplantation of cells and their nucleus on model alimentary dislipoproteinemia. Experiment is executed on the rabbits containing on an atherogenous diet. In blood serum of animals studied changes of a lipide exchange, in a liver — level of stresses-proteins, morphological changes and the maintenance of markers of an apoptosis and a proliferation. Also estimated the area of atherogenous plaques and a thickness of intima of an aorta. It is shown that unlike cellular transplantation, introduction of nucleus led to more expressed therapeutic effect and inhibition of expansion of leading links of an atherogenesis. |
| first_indexed | 2024-04-10T01:09:53Z |
| format | Article |
| id | doaj.art-83529bab949b420b93f90fe1fa41c777 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:09:53Z |
| publishDate | 2011-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-83529bab949b420b93f90fe1fa41c7772023-03-13T09:58:16ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-12-01106232910.20538/1682-0363-2011-6-23-291002Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia modelYu. I. Pivovarov0T. Ye. Kurilskaya1A. S. Sergeyeva2I. V. Babushkina3B. K. Baduyev4G. B. Borovsky5Научный центр реконструктивной и восстановительной хирургии СО РАМННаучный центр реконструктивной и восстановительной хирургии СО РАМННаучный центр реконструктивной и восстановительной хирургии СО РАМННаучный центр реконструктивной и восстановительной хирургии СО РАМНСибирский институт физиологии и биохимии растений СО РАНСибирский институт физиологии и биохимии растений СО РАНResearch objective was to compare effects of transplantation of cells and their nucleus on model alimentary dislipoproteinemia. Experiment is executed on the rabbits containing on an atherogenous diet. In blood serum of animals studied changes of a lipide exchange, in a liver — level of stresses-proteins, morphological changes and the maintenance of markers of an apoptosis and a proliferation. Also estimated the area of atherogenous plaques and a thickness of intima of an aorta. It is shown that unlike cellular transplantation, introduction of nucleus led to more expressed therapeutic effect and inhibition of expansion of leading links of an atherogenesis.https://bulletin.ssmu.ru/jour/article/view/1496трансплантация клеток и ядердислипидемия |
| spellingShingle | Yu. I. Pivovarov T. Ye. Kurilskaya A. S. Sergeyeva I. V. Babushkina B. K. Baduyev G. B. Borovsky Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model Бюллетень сибирской медицины трансплантация клеток и ядер дислипидемия |
| title | Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model |
| title_full | Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model |
| title_fullStr | Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model |
| title_full_unstemmed | Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model |
| title_short | Sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model |
| title_sort | sanogenetic mechanisms of transplantation action of the whole cells and their nuclear fraction on experimental dislipoproteinemia model |
| topic | трансплантация клеток и ядер дислипидемия |
| url | https://bulletin.ssmu.ru/jour/article/view/1496 |
| work_keys_str_mv | AT yuipivovarov sanogeneticmechanismsoftransplantationactionofthewholecellsandtheirnuclearfractiononexperimentaldislipoproteinemiamodel AT tyekurilskaya sanogeneticmechanismsoftransplantationactionofthewholecellsandtheirnuclearfractiononexperimentaldislipoproteinemiamodel AT assergeyeva sanogeneticmechanismsoftransplantationactionofthewholecellsandtheirnuclearfractiononexperimentaldislipoproteinemiamodel AT ivbabushkina sanogeneticmechanismsoftransplantationactionofthewholecellsandtheirnuclearfractiononexperimentaldislipoproteinemiamodel AT bkbaduyev sanogeneticmechanismsoftransplantationactionofthewholecellsandtheirnuclearfractiononexperimentaldislipoproteinemiamodel AT gbborovsky sanogeneticmechanismsoftransplantationactionofthewholecellsandtheirnuclearfractiononexperimentaldislipoproteinemiamodel |