Development and Characterization of Anti-<i>Naja ashei</i> Three-Finger Toxins (3FTxs)-Specific Monoclonal Antibodies and Evaluation of Their In Vitro Inhibition Activity

Development and Characterization of Anti-<i>Naja ashei</i> Three-Finger Toxins (3FTxs)-Specific Monoclonal Antibodies and Evaluation of Their In Vitro Inhibition Activity

Antivenom immunotherapy is the mainstay of treatment for snakebite envenoming. Most parts of the world affected by snakebite envenoming depend on broad-spectrum polyspecific antivenoms that are known to contain a low content of case-specific efficacious immunoglobulins. Thus, advances in toxin-speci...

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Bibliographic Details
Main Authors: Ernest Z. Manson, Mutinda C. Kyama, Josephine Kimani, Aleksandra Bocian, Konrad K. Hus, Vladimír Petrilla, Jaroslav Legáth, James H. Kimotho
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Toxins
Subjects:
<i>Naja ashei</i>
three-finger toxins
monoclonal antibodies
snakebite envenoming
inhibition ELISA
Online Access:https://www.mdpi.com/2072-6651/14/4/285

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