Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus
Summary: To analyze the differences between different-sized Acipenser dabryanus, we randomly selected 600 3-month-old A. dabryanus juveniles. Four months later, the blood and white muscle of these fish were analyzed. The results showed no significant difference in the length-weight relationship (LWR...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-08-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223014906 |
| _version_ | 1797768216195366912 |
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| author | Xiaoyun Wu Jiansheng Lai Yeyu Chen Ya Liu Mingjiang Song Feiyang Li Pengcheng Li Qingzhi Li Quan Gong |
| author_facet | Xiaoyun Wu Jiansheng Lai Yeyu Chen Ya Liu Mingjiang Song Feiyang Li Pengcheng Li Qingzhi Li Quan Gong |
| author_sort | Xiaoyun Wu |
| collection | DOAJ |
| description | Summary: To analyze the differences between different-sized Acipenser dabryanus, we randomly selected 600 3-month-old A. dabryanus juveniles. Four months later, the blood and white muscle of these fish were analyzed. The results showed no significant difference in the length-weight relationship (LWR) b value between the large and small A. dabryanus. The levels of serum growth hormone (gh) and insulin-like growth factor 1 (igf1) in the large A. dabryanus were significantly lower than those in the small, whereas the activity levels of Total superoxide dismutase (T-sod) and catalase (cat) were opposite to the results of gh and igf1. A total of 212 and 245 metabolites showed significant changes in the positive and negative polarity mode, respectively. Among 3,308 proteins identified, 69 proteins showed upregulated expression, and 185 proteins showed downregulated expression. These results indicated that the growth advantage of A. dabryanus was closely related to glycolysis, protein synthesis, and antioxidant function. |
| first_indexed | 2024-03-12T20:50:14Z |
| format | Article |
| id | doaj.art-83575936467744ce99a59e7afddfded9 |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-03-12T20:50:14Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-83575936467744ce99a59e7afddfded92023-08-01T04:08:59ZengElsevieriScience2589-00422023-08-01268107413Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanusXiaoyun Wu0Jiansheng Lai1Yeyu Chen2Ya Liu3Mingjiang Song4Feiyang Li5Pengcheng Li6Qingzhi Li7Quan Gong8The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, ChinaThe Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, ChinaThe Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, ChinaThe Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, ChinaThe Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, ChinaThe Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, ChinaThe Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, ChinaThe Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, ChinaThe Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China; Corresponding authorSummary: To analyze the differences between different-sized Acipenser dabryanus, we randomly selected 600 3-month-old A. dabryanus juveniles. Four months later, the blood and white muscle of these fish were analyzed. The results showed no significant difference in the length-weight relationship (LWR) b value between the large and small A. dabryanus. The levels of serum growth hormone (gh) and insulin-like growth factor 1 (igf1) in the large A. dabryanus were significantly lower than those in the small, whereas the activity levels of Total superoxide dismutase (T-sod) and catalase (cat) were opposite to the results of gh and igf1. A total of 212 and 245 metabolites showed significant changes in the positive and negative polarity mode, respectively. Among 3,308 proteins identified, 69 proteins showed upregulated expression, and 185 proteins showed downregulated expression. These results indicated that the growth advantage of A. dabryanus was closely related to glycolysis, protein synthesis, and antioxidant function.http://www.sciencedirect.com/science/article/pii/S2589004223014906IchthyologyProteomicsMetabolomics |
| spellingShingle | Xiaoyun Wu Jiansheng Lai Yeyu Chen Ya Liu Mingjiang Song Feiyang Li Pengcheng Li Qingzhi Li Quan Gong Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus iScience Ichthyology Proteomics Metabolomics |
| title | Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus |
| title_full | Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus |
| title_fullStr | Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus |
| title_full_unstemmed | Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus |
| title_short | Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus |
| title_sort | combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in acipenser dabryanus |
| topic | Ichthyology Proteomics Metabolomics |
| url | http://www.sciencedirect.com/science/article/pii/S2589004223014906 |
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