Nomogram Predicting the Benefits of Adding Concurrent Chemotherapy to Intensity-Modulated Radiotherapy After Induction Chemotherapy in Stages II–IVb Nasopharyngeal Carcinoma

Nomogram Predicting the Benefits of Adding Concurrent Chemotherapy to Intensity-Modulated Radiotherapy After Induction Chemotherapy in Stages II–IVb Nasopharyngeal Carcinoma

BackgroundTo compare the efficacy of induction chemotherapy plus concurrent chemoradiotherapy (IC+CCRT) versus induction chemotherapy plus radiotherapy (IC+RT) in patients with locoregionally advanced nasopharyngeal carcinoma (NPC).Patients and MethodsOne thousand three hundred twenty four patients...

Full description

Bibliographic Details
Main Authors:	Sai-Lan Liu, Xue-Song Sun, Zi-Jian Lu, Qiu-Yan Chen, Huan-Xin Lin, Lin-Quan Tang, Jin-Xin Bei, Ling Guo, Hai-Qiang Mai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Series:	Frontiers in Oncology
Subjects:	nasopharyngeal carcinoma (NPC) induction chemotherapy (IC) concurrent chemoradiotherapy radiotherapy nomogram
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2020.539321/full

Similar Items

Stratification of Candidates for Induction Chemotherapy in Stage III-IV Nasopharyngeal Carcinoma: A Large Cohort Study Based on a Comprehensive Prognostic Model
by: Xue-Song Sun, et al.
Published: (2020-02-01)

Establishment and validation of two nomograms to predict the benefit of concurrent chemotherapy in stage II‐IVa nasopharyngeal carcinoma patients with different risk factors: Analysis based on a large cohort
by: Xue‐Song Sun, et al.
Published: (2020-03-01)

Comparison of Gemcitabine Plus Cisplatin vs. Docetaxel Plus Fluorouracil Plus Cisplatin Palliative Chemotherapy for Metastatic Nasopharyngeal Carcinoma
by: Xue-Song Sun, et al.
Published: (2020-08-01)

Longitudinal Trend of Health-Related Quality of Life During Concurrent Chemoradiotherapy and Survival in Patients With Stage II–IVb Nasopharyngeal Carcinoma
by: Ji-Bin Li, et al.
Published: (2020-10-01)

M1 stage subdivisions based on F-FDG PET-CT parameters to identify locoregional radiotherapy for metastatic nasopharyngeal carcinoma
by: Hui-Zhi Qiu, et al.
Published: (2022-08-01)

Liposomal paclitaxel versus docetaxel in induction chemotherapy using Taxanes, cisplatin and 5-fluorouracil for locally advanced nasopharyngeal carcinoma
by: Sai-Lan Liu, et al.
Published: (2018-12-01)

Paclitaxel liposome, cisplatin and 5-fluorouracil-based induction chemotherapy followed by de-escalated intensity-modulated radiotherapy with concurrent cisplatin in stage IVA–IVB childhood nasopharyngeal carcinoma in endemic area: a phase II, single-arm trialResearch in context
by: Dong-Hua Luo, et al.
Published: (2023-11-01)

Comparing three induction chemotherapy regimens for patients with locoregionally advanced nasopharyngeal carcinoma based on TNM stage and plasma Epstein–Barr virus DNA level
by: Sai-Lan Liu, et al.
Published: (2020-02-01)

Induction chemotherapy followed by radiotherapy concurrent chemoradiotherapy in the treatment of different risk locoregionally advanced nasopharyngeal carcinoma
by: Li-Ting Liu, et al.
Published: (2020-06-01)

Concurrent chemoradiotherapy with or without cetuximab for stage II to IVb nasopharyngeal carcinoma: a case–control study
by: Yang Li, et al.
Published: (2017-08-01)

Individualized concurrent chemotherapy by pretreatment plasma Epstein‐Barr viral DNA in II‐III stage nasopharyngeal carcinoma: A propensity score matching analysis using a large cohort
by: Xue‐Song Sun, et al.
Published: (2019-08-01)

Inhibition of NPC1L1 disrupts adaptive responses of drug‐tolerant persister cells to chemotherapy
by: Zhe Zhang, et al.
Published: (2022-02-01)

Identifying optimal candidates for postoperative adjuvant therapy among regional persistent/recurrent nasopharyngeal carcinoma patients after neck dissection
by: Sai-Lan Liu, et al.
Published: (2022-11-01)

The diagnostic and prognostic values of plasma Epstein-Barr virus DNA for residual cervical lymphadenopathy in nasopharyngeal carcinoma patients: a retrospective study
by: Sai-Lan Liu, et al.
Published: (2019-03-01)

Prognosis of Extracapsular Spread of Cervical Lymph Node Metastases in Nasopharyngeal Carcinoma
by: Xue Yin, et al.
Published: (2020-09-01)

A retrospective study of concurrent chemoradiotherapy plus S-1 adjuvant chemotherapy on curative effect for treatment of patients with N3 stage nasopharyngeal carcinoma
by: Zhang S, et al.
Published: (2018-06-01)

Optimal sequencing of chemotherapy with chemoradiotherapy based on TNM stage classification and EBV DNA in locoregionally advanced nasopharyngeal carcinoma
by: Li-Ting Liu, et al.
Published: (2019-10-01)

First-Line Immunochemotherapy Versus Palliative Chemotherapy Plus Definitive Radiation Therapy for Metastatic Nasopharyngeal Carcinoma: A Matched Cohort Study
by: Zhen-Chong Yang, et al.
Published: (2022-08-01)

ATR activated by EB virus facilitates chemotherapy resistance to cisplatin or 5-fluorouracil in human nasopharyngeal carcinoma
by: Zhang B, et al.
Published: (2019-01-01)

A Therapeutic Approach to Nasopharyngeal Carcinomas by DNAzymes Targeting EBV LMP-1 Gene
by: Lun-Quan Sun, et al.
Published: (2010-09-01)

Induction chemotherapy with paclitaxel, carboplatin and cetuximab for locoregionally advanced nasopharyngeal carcinoma: A single-center, retrospective study
by: Naohiro Takeshita, et al.
Published: (2022-08-01)

Intensive Local Radiotherapy Is Associated With Better Local Control and Prolonged Survival in Bone-Metastatic Nasopharyngeal Carcinoma Patients
by: Xiao-Yun Li, et al.
Published: (2020-03-01)

Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma
by: Shan-Shan Guo, et al.
Published: (2021-08-01)

mRNA‐based Vaccines Targeting the T‐cell Epitope‐rich Domain of Epstein Barr Virus Latent Proteins Elicit Robust Anti‐Tumor Immunity in Mice
by: Ge‐Xin Zhao, et al.
Published: (2023-12-01)

Association of public health insurance with cancer-specific mortality risk among patients with nasopharyngeal carcinoma: a prospective cohort study in China
by: Dan Li, et al.
Published: (2023-06-01)

Hyperthermic intraoperative thoracoabdominal chemotherapy for stage IVB epithelial ovarian carcinoma
by: Alexandre Brind'Amour, et al.
Published: (2020-11-01)

Modeling and Analysis of Voltage Harmonic for Three-Level Neutral-Point-Clamped H-Bridge Inverter Considering Dead-Time
by: Wen-Jie Wu, et al.
Published: (2022-08-01)

Comparing the efficacy and safety of cisplatin and other platinum-based chemotherapies in locally advanced nasopharyngeal carcinoma: a systematic review and meta-analysis
by: Zhiru Li, et al.
Published: (2022-06-01)

Genetic variations in radiation and chemotherapy drug action pathways and survival in locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy.
by: Huai Liu, et al.
Published: (2013-01-01)

Induction Chemotherapy Combined With Intensity-Modulated Radiotherapy for 129 Nasopharyngeal Carcinoma Patients With Synchronous Metastases: A Retrospective Study
by: Mengshan Ni, et al.
Published: (2021-05-01)

Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis
by: Sheng-Dean Luo, et al.
Published: (2022-07-01)

Clinical characteristics and prognostic factors affecting survival after radical radiotherapy for early and late post-treatment metastatic nasopharyngeal carcinoma
by: Guo-Dong Jia, et al.
Published: (2023-01-01)

Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer
by: Hoi-Lam Ngan, et al.
Published: (2018-06-01)

Lipocalin 2 Reduces MET Levels by Inhibiting MEK/ERK Signaling to Inhibit Nasopharyngeal Carcinoma Cell Migration
by: Ju-Pi Li, et al.
Published: (2022-11-01)

Mannose 6-phosphate receptors, Niemann-Pick C2 protein, and lysosomal cholesterol accumulation
by: Marion Willenborg, et al.
Published: (2005-12-01)

Comparison of Therapeutic Efficacy between Gastrectomy with Transarterial Chemoembolization Plus Systemic Chemotherapy and Systemic Chemotherapy Alone in Gastric Cancer with Synchronous Liver Metastasis
by: Sen-Feng Liu, et al.
Published: (2015-01-01)

Maximal standard uptake values of 18F-fluoro-2-deoxy-D-glucose positron emission tomography compared with Epstein-Barr virus DNA as prognostic indicators in de novo metastatic nasopharyngeal carcinoma patients
by: Xue-Song Sun, et al.
Published: (2019-09-01)

Identification of two microRNA signatures in whole blood as novel biomarkers for diagnosis of nasopharyngeal carcinoma
by: Wen Wen, et al.
Published: (2019-06-01)

Adding Concurrent Chemotherapy Significantly Improves the Survival of Stage II-IVb Nasopharyngeal Carcinoma Patients Treated With Concurrent Anti-EGFR Agents
by: Zi-Kun Yu, et al.
Published: (2021-12-01)

Bile acids at neutral and acidic pH induce apoptosis and gene cleavages in nasopharyngeal epithelial cells: implications in chromosome rearrangement
by: Sang-Nee Tan, et al.
Published: (2018-04-01)