Connective tissue growth factor promotes cementogenesis and cementum repair via Cx43/β-catenin axis

Abstract Background Orthodontic tooth movement inevitably induces cementum resorption, which is an urgent problem for orthodontists to confront. Human periodontal ligament stem cells (hPDLSCs) exert an important role in the orthodontic tooth movement and exhibit multidirectional differentiation abil...

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Bibliographic Details
Main Authors: Zuping Wu, Yuying He, Sirui Chen, Li Zhu, Jiahe Wang, Demao Zhang, Jing Xie, Shujuan Zou, Chenchen Zhou
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-022-03149-8