Gut microbiome, metabolome, and allergic diseases
The number of patients with allergic and inflammatory disorders has been increasing during the past several decades. Accumulating evidence has refined our understanding of the relationship between allergic diseases and the gut microbiome. In addition, the gut microbiome is now known to produce both...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-10-01
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| Series: | Allergology International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893017300862 |
| _version_ | 1811338533619630080 |
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| author | So-ichiro Hirata Jun Kunisawa |
| author_facet | So-ichiro Hirata Jun Kunisawa |
| author_sort | So-ichiro Hirata |
| collection | DOAJ |
| description | The number of patients with allergic and inflammatory disorders has been increasing during the past several decades. Accumulating evidence has refined our understanding of the relationship between allergic diseases and the gut microbiome. In addition, the gut microbiome is now known to produce both useful and harmful metabolites from dietary materials. These metabolites and bacterial components help to regulate host immune responses and potentially affect the development of allergic diseases. Here, we describe recent findings regarding the immunologic crosstalk between commensal bacteria and dietary components in the regulation of host immunity and the influence of this relationship on the development of allergic diseases. |
| first_indexed | 2024-04-13T18:12:20Z |
| format | Article |
| id | doaj.art-835cb27c683f441ca8094491668d5158 |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-04-13T18:12:20Z |
| publishDate | 2017-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-835cb27c683f441ca8094491668d51582022-12-22T02:35:51ZengElsevierAllergology International1323-89302017-10-0166452352810.1016/j.alit.2017.06.008Gut microbiome, metabolome, and allergic diseasesSo-ichiro Hirata0Jun Kunisawa1Laboratory of Vaccine Materials and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, JapanLaboratory of Vaccine Materials and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, JapanThe number of patients with allergic and inflammatory disorders has been increasing during the past several decades. Accumulating evidence has refined our understanding of the relationship between allergic diseases and the gut microbiome. In addition, the gut microbiome is now known to produce both useful and harmful metabolites from dietary materials. These metabolites and bacterial components help to regulate host immune responses and potentially affect the development of allergic diseases. Here, we describe recent findings regarding the immunologic crosstalk between commensal bacteria and dietary components in the regulation of host immunity and the influence of this relationship on the development of allergic diseases.http://www.sciencedirect.com/science/article/pii/S1323893017300862Amino acidLipidsMicrobiomeShort-chain fatty acidVitamin |
| spellingShingle | So-ichiro Hirata Jun Kunisawa Gut microbiome, metabolome, and allergic diseases Allergology International Amino acid Lipids Microbiome Short-chain fatty acid Vitamin |
| title | Gut microbiome, metabolome, and allergic diseases |
| title_full | Gut microbiome, metabolome, and allergic diseases |
| title_fullStr | Gut microbiome, metabolome, and allergic diseases |
| title_full_unstemmed | Gut microbiome, metabolome, and allergic diseases |
| title_short | Gut microbiome, metabolome, and allergic diseases |
| title_sort | gut microbiome metabolome and allergic diseases |
| topic | Amino acid Lipids Microbiome Short-chain fatty acid Vitamin |
| url | http://www.sciencedirect.com/science/article/pii/S1323893017300862 |
| work_keys_str_mv | AT soichirohirata gutmicrobiomemetabolomeandallergicdiseases AT junkunisawa gutmicrobiomemetabolomeandallergicdiseases |