Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary results
There are individuals who have a progressive language deficit without presenting cognitive deficits in other areas. One of the diseases related to this presentation is primary progressive aphasia (PPA). OBJECTIVE: Identify by means of diffusion tensor imaging (DTI) and measurements of cortical volum...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
2011-06-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000400007&lng=en&tlng=en |
| _version_ | 1818307307575967744 |
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| author | Fábio Pascotto de Oliveira Jaderson Costa da Costa Sabine Possa Marroni Ana Maria Marques da Silva Sthefanie Hansen Barreiro Fábio Kunihiro Maeda Mirna Wetters Portuguez |
| author_facet | Fábio Pascotto de Oliveira Jaderson Costa da Costa Sabine Possa Marroni Ana Maria Marques da Silva Sthefanie Hansen Barreiro Fábio Kunihiro Maeda Mirna Wetters Portuguez |
| author_sort | Fábio Pascotto de Oliveira |
| collection | DOAJ |
| description | There are individuals who have a progressive language deficit without presenting cognitive deficits in other areas. One of the diseases related to this presentation is primary progressive aphasia (PPA). OBJECTIVE: Identify by means of diffusion tensor imaging (DTI) and measurements of cortical volume, brain areas that lead to dysphasia when presenting signs of impaired connectivity or reduced volume. METHOD: Four patients with PPA were evaluated using DTI, and measurements of cortical volumes in temporal areas. These patients were compared with two normal volunteers. RESULTS: There is a trend to a difference in the number and volume of related fibers between control group and patients with PPA. Comparing cortical volumes in temporal areas between groups yielded a trend to a smaller volume in PPA patients. CONCLUSION: Patients with PPA have a trend to impairment in cortical and subcortical levels regarding relevant areas. |
| first_indexed | 2024-12-13T06:56:18Z |
| format | Article |
| id | doaj.art-835d3e3d5e584d068f800a3d144d749f |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-13T06:56:18Z |
| publishDate | 2011-06-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-835d3e3d5e584d068f800a3d144d749f2022-12-21T23:56:01ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272011-06-0169344645110.1590/S0004-282X2011000400007S0004-282X2011000400007Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary resultsFábio Pascotto de Oliveira0Jaderson Costa da Costa1Sabine Possa Marroni2Ana Maria Marques da Silva3Sthefanie Hansen Barreiro4Fábio Kunihiro Maeda5Mirna Wetters Portuguez6HUSMPontifícia Universidade Católica do Rio Grande do SulPontifícia Universidade Católica do Rio Grande do SulHUSMPontifícia Universidade Católica do Rio Grande do SulPontifícia Universidade Católica do Rio Grande do SulPontifícia Universidade Católica do Rio Grande do SulThere are individuals who have a progressive language deficit without presenting cognitive deficits in other areas. One of the diseases related to this presentation is primary progressive aphasia (PPA). OBJECTIVE: Identify by means of diffusion tensor imaging (DTI) and measurements of cortical volume, brain areas that lead to dysphasia when presenting signs of impaired connectivity or reduced volume. METHOD: Four patients with PPA were evaluated using DTI, and measurements of cortical volumes in temporal areas. These patients were compared with two normal volunteers. RESULTS: There is a trend to a difference in the number and volume of related fibers between control group and patients with PPA. Comparing cortical volumes in temporal areas between groups yielded a trend to a smaller volume in PPA patients. CONCLUSION: Patients with PPA have a trend to impairment in cortical and subcortical levels regarding relevant areas.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000400007&lng=en&tlng=enanomiaafasia primária progressivaDTItratografiavolume cerebralfascículo arqueadolinguagem |
| spellingShingle | Fábio Pascotto de Oliveira Jaderson Costa da Costa Sabine Possa Marroni Ana Maria Marques da Silva Sthefanie Hansen Barreiro Fábio Kunihiro Maeda Mirna Wetters Portuguez Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary results Arquivos de Neuro-Psiquiatria anomia afasia primária progressiva DTI tratografia volume cerebral fascículo arqueado linguagem |
| title | Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary results |
| title_full | Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary results |
| title_fullStr | Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary results |
| title_full_unstemmed | Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary results |
| title_short | Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary results |
| title_sort | primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry preliminary results |
| topic | anomia afasia primária progressiva DTI tratografia volume cerebral fascículo arqueado linguagem |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000400007&lng=en&tlng=en |
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