Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme

Indeterminate HIV PCR results represent missed diagnostic opportunities within South Africa's early infant diagnosis (EID) programme. These results not only delay diagnosis and appropriate management but are also a source of confusion and apprehension amongst clinicians and caregivers. We descr...

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Main Authors: Ahmad Haeri Mazanderani, Karl-Günter Technau, Nei-yuan Hsiao, Jean Maritz, Sergio Carmona, Gayle G. Sherman
Format: Article
Language:English
Published: AOSIS 2016-05-01
Series:Southern African Journal of HIV Medicine
Subjects:
Online Access:https://sajhivmed.org.za/index.php/hivmed/article/view/451
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author Ahmad Haeri Mazanderani
Karl-Günter Technau
Nei-yuan Hsiao
Jean Maritz
Sergio Carmona
Gayle G. Sherman
author_facet Ahmad Haeri Mazanderani
Karl-Günter Technau
Nei-yuan Hsiao
Jean Maritz
Sergio Carmona
Gayle G. Sherman
author_sort Ahmad Haeri Mazanderani
collection DOAJ
description Indeterminate HIV PCR results represent missed diagnostic opportunities within South Africa's early infant diagnosis (EID) programme. These results not only delay diagnosis and appropriate management but are also a source of confusion and apprehension amongst clinicians and caregivers. We describe the extent of indeterminate HIV PCR results within South Africa's EID programme and provide recommendations for the management of these cases, both in terms of laboratory practice and the clinical care of the infants. Keywords: EID; HIV PCR; Indeterminate
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spelling doaj.art-835df6e80df24eec9bd12d1268d822fc2022-12-22T02:10:39ZengAOSISSouthern African Journal of HIV Medicine1608-96932078-67512016-05-01171e1e510.4102/sajhivmed.v17i1.451524Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programmeAhmad Haeri Mazanderani0Karl-Günter Technau1Nei-yuan Hsiao2Jean Maritz3Sergio Carmona4Gayle G. Sherman5Centre for HIV & STIs, National Institute for Communicable Diseases; Department of Medical Virology, University of PretoriaEmpilweni Services and Research Unit, Johannesburg; Department of Paediatrics and Child Health, University of the WitwatersrandDivision of Medical Virology, University of Cape Town; National Health Laboratory ServiceNational Health Laboratory Service; Division of Medical Virology, Department of Pathology, Stellenbosch University, South AfricaNational Health Laboratory Service; Department of Molecular Medicine and Haematology, University of the WitwatersrandCentre for HIV & STIs, National Institute for Communicable Diseases; Department of Paediatrics and Child Health, University of the WitwatersrandIndeterminate HIV PCR results represent missed diagnostic opportunities within South Africa's early infant diagnosis (EID) programme. These results not only delay diagnosis and appropriate management but are also a source of confusion and apprehension amongst clinicians and caregivers. We describe the extent of indeterminate HIV PCR results within South Africa's EID programme and provide recommendations for the management of these cases, both in terms of laboratory practice and the clinical care of the infants. Keywords: EID; HIV PCR; Indeterminatehttps://sajhivmed.org.za/index.php/hivmed/article/view/451EIDHIV PCRIndeterminate
spellingShingle Ahmad Haeri Mazanderani
Karl-Günter Technau
Nei-yuan Hsiao
Jean Maritz
Sergio Carmona
Gayle G. Sherman
Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme
Southern African Journal of HIV Medicine
EID
HIV PCR
Indeterminate
title Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme
title_full Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme
title_fullStr Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme
title_full_unstemmed Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme
title_short Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme
title_sort recommendations for the management of indeterminate hiv pcr results within south africa s early infant diagnosis programme
topic EID
HIV PCR
Indeterminate
url https://sajhivmed.org.za/index.php/hivmed/article/view/451
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