Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract
Prasman leaves (Eupatororium triplinerve V) was well documented to have anti cancer benefit in Indonesian traditional medicine history. However, there were no scientific studies including toxicological assessment on the plan extract. The purpose of this study was to investigate the toxicological eff...
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| Format: | Article |
| Language: | English |
| Published: |
Indonesian Society for Cancer Chemoprevention
2011-02-01
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| Series: | ISCC (Indonesian Journal of Cancer Chemoprevention) |
| Online Access: | https://ijcc.chemoprev.org/index.php/ijcc/article/view/31 |
| _version_ | 1828824393823813632 |
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| author | Shirly Kumala Dwi Windi Sapitri |
| author_facet | Shirly Kumala Dwi Windi Sapitri |
| author_sort | Shirly Kumala |
| collection | DOAJ |
| description | Prasman leaves (Eupatororium triplinerve V) was well documented to have anti cancer benefit in Indonesian traditional medicine history. However, there were no scientific studies including toxicological assessment on the plan extract. The purpose of this study was to investigate the toxicological effect of some fractions of Prasman leaves methanol extract. Phytochemical screening by the Farnsworth method on powder and some fraction of the methanol extract were conducted followed by toxicity test using the “Brine Shrimp Lethality” test (BSLT) method. In the current study results, the phytochemical screening showed the presence of flavonoid, saponin, coumarin, tannin, steroid and volatile oil. LC50 of the n-hexane fraction 238.66 µg/mL, ethyl acetate fraction 24.42 µg/mL, and n-butanol 64.10 µg/mL.
Keywords : BSLT, Toxicity test, Eupatororium triplinerve |
| first_indexed | 2024-12-12T13:55:31Z |
| format | Article |
| id | doaj.art-835e74ca795948e0b1f28286e0371c32 |
| institution | Directory Open Access Journal |
| issn | 2088-0197 2355-8989 |
| language | English |
| last_indexed | 2024-12-12T13:55:31Z |
| publishDate | 2011-02-01 |
| publisher | Indonesian Society for Cancer Chemoprevention |
| record_format | Article |
| series | ISCC (Indonesian Journal of Cancer Chemoprevention) |
| spelling | doaj.art-835e74ca795948e0b1f28286e0371c322022-12-22T00:22:28ZengIndonesian Society for Cancer ChemopreventionISCC (Indonesian Journal of Cancer Chemoprevention)2088-01972355-89892011-02-012119319710.14499/indonesianjcanchemoprev2iss1pp193-19732Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) ExtractShirly Kumala0Dwi Windi Sapitri1Faculty of Pharmacy, Pancasila UniversityFaculty of Pharmacy, Pancasila UniversityPrasman leaves (Eupatororium triplinerve V) was well documented to have anti cancer benefit in Indonesian traditional medicine history. However, there were no scientific studies including toxicological assessment on the plan extract. The purpose of this study was to investigate the toxicological effect of some fractions of Prasman leaves methanol extract. Phytochemical screening by the Farnsworth method on powder and some fraction of the methanol extract were conducted followed by toxicity test using the “Brine Shrimp Lethality” test (BSLT) method. In the current study results, the phytochemical screening showed the presence of flavonoid, saponin, coumarin, tannin, steroid and volatile oil. LC50 of the n-hexane fraction 238.66 µg/mL, ethyl acetate fraction 24.42 µg/mL, and n-butanol 64.10 µg/mL. Keywords : BSLT, Toxicity test, Eupatororium triplinervehttps://ijcc.chemoprev.org/index.php/ijcc/article/view/31 |
| spellingShingle | Shirly Kumala Dwi Windi Sapitri Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract ISCC (Indonesian Journal of Cancer Chemoprevention) |
| title | Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract |
| title_full | Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract |
| title_fullStr | Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract |
| title_full_unstemmed | Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract |
| title_short | Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract |
| title_sort | phytochemical screening and toxicological evaluation using brine shrimp lethality test bslt of some fractions of prasman leaves eupatorium triplinerve v extract |
| url | https://ijcc.chemoprev.org/index.php/ijcc/article/view/31 |
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