Phosphorylation of Tau at S422 is enhanced by Aβ in TauPS2APP triple transgenic mice

Phosphorylation of Tau at S422 is enhanced by Aβ in TauPS2APP triple transgenic mice

Amyloid beta peptides and microtubule-associated protein Tau are misfolded and form aggregates in brains of Alzheimer's disease patients. To examine their specific roles in the pathogenesis of Alzheimer's disease and their relevance in neurodegenerative processes, we have created TauPS2APP...

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Bibliographic Details
Main Authors: Fiona Grueninger, Bernd Bohrmann, Christian Czech, Theresa Maria Ballard, Johann R. Frey, Claudia Weidensteiner, Markus von Kienlin, Laurence Ozmen
Format: Article
Language:English
Published: Elsevier 2010-02-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
TauPS2APP
Transgenic
Tau
Phosphorylation
Aβ
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109002459

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