Radiation Therapy For The Solitary Plasmacytoma

Plasma-cell neoplasms are classically categorized into four groups as: multiple myeloma (MM), plasma-cell leukemias, solitary plasmacytomas (SP) of the bone (SPB), and extramedullary plasmacytomas (EMP). These tumors may be described as localized or diffuse in presentation. Localized plasma-cell ne...

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Main Authors: Esengül Koçak, Giorgio Ballerini, Abderrahim Zouhair, Mahmut Özşahin
Format: Article
Language:English
Published: Galenos Publishing House 2010-06-01
Series:Turkish Journal of Hematology
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-88319
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author Esengül Koçak
Giorgio Ballerini
Abderrahim Zouhair
Mahmut Özşahin
author_facet Esengül Koçak
Giorgio Ballerini
Abderrahim Zouhair
Mahmut Özşahin
author_sort Esengül Koçak
collection DOAJ
description Plasma-cell neoplasms are classically categorized into four groups as: multiple myeloma (MM), plasma-cell leukemias, solitary plasmacytomas (SP) of the bone (SPB), and extramedullary plasmacytomas (EMP). These tumors may be described as localized or diffuse in presentation. Localized plasma-cell neoplasms are rare, and include SP of the skeletal system, accounting for 2-5% of all plasma-cell neoplasms, and EMP of soft tissue, accounting for approximately 3% of all such neoplasms. SP is defined as a solitary mass of neoplastic plasma cells either in the bone marrow or in various soft tissue sites. There appears to be a continuum in which SP often progresses to MM. The main treatment modality for SP is radiation therapy (RT). However, there are no conclusive data in the literature on the optimal RT dose for SP. This review describes the interrelationship of plasma-cell neoplasms, and attempts to determine the minimal RT dose required to obtain local control.
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spelling doaj.art-83615957e1834017a8f23753b61dbdea2023-02-15T16:16:48ZengGalenos Publishing HouseTurkish Journal of Hematology1308-52632010-06-01272576110.5152/tjh.2010.01TJH-88319Radiation Therapy For The Solitary PlasmacytomaEsengül Koçak0Giorgio Ballerini1Abderrahim Zouhair2Mahmut Özşahin3Departments Of Radiation Oncology, University Of Lausanne Medical Center, Lausanne, SwitzerlandDepartments Of Radiation Oncology, University Of Lausanne Medical Center, Lausanne, SwitzerlandDepartments Of Radiation Oncology, University Of Lausanne Medical Center, Lausanne, SwitzerlandDepartments Of Radiation Oncology, University Of Lausanne Medical Center, Lausanne, SwitzerlandPlasma-cell neoplasms are classically categorized into four groups as: multiple myeloma (MM), plasma-cell leukemias, solitary plasmacytomas (SP) of the bone (SPB), and extramedullary plasmacytomas (EMP). These tumors may be described as localized or diffuse in presentation. Localized plasma-cell neoplasms are rare, and include SP of the skeletal system, accounting for 2-5% of all plasma-cell neoplasms, and EMP of soft tissue, accounting for approximately 3% of all such neoplasms. SP is defined as a solitary mass of neoplastic plasma cells either in the bone marrow or in various soft tissue sites. There appears to be a continuum in which SP often progresses to MM. The main treatment modality for SP is radiation therapy (RT). However, there are no conclusive data in the literature on the optimal RT dose for SP. This review describes the interrelationship of plasma-cell neoplasms, and attempts to determine the minimal RT dose required to obtain local control.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-88319solitary plasmacytomaradiotherapymultiple myelomamanagement
spellingShingle Esengül Koçak
Giorgio Ballerini
Abderrahim Zouhair
Mahmut Özşahin
Radiation Therapy For The Solitary Plasmacytoma
Turkish Journal of Hematology
solitary plasmacytoma
radiotherapy
multiple myeloma
management
title Radiation Therapy For The Solitary Plasmacytoma
title_full Radiation Therapy For The Solitary Plasmacytoma
title_fullStr Radiation Therapy For The Solitary Plasmacytoma
title_full_unstemmed Radiation Therapy For The Solitary Plasmacytoma
title_short Radiation Therapy For The Solitary Plasmacytoma
title_sort radiation therapy for the solitary plasmacytoma
topic solitary plasmacytoma
radiotherapy
multiple myeloma
management
url https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-88319
work_keys_str_mv AT esengulkocak radiationtherapyforthesolitaryplasmacytoma
AT giorgioballerini radiationtherapyforthesolitaryplasmacytoma
AT abderrahimzouhair radiationtherapyforthesolitaryplasmacytoma
AT mahmutozsahin radiationtherapyforthesolitaryplasmacytoma