IGLR-2, a Leucine-Rich Repeat Domain Containing Protein, Is Required for the Host Defense in Caenorhabditis elegans

IGLR-2, a Leucine-Rich Repeat Domain Containing Protein, Is Required for the Host Defense in Caenorhabditis elegans

Enterohemorrhagic Escherichia coli (EHEC), a human pathogen, also infects Caenorhabditis elegans. We demonstrated previously that C. elegans activates the p38 MAPK innate immune pathway to defend against EHEC infection. However, whether a C. elegans pattern recognition receptor (PRR) exists to regul...

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Bibliographic Details
Main Authors: Cheng-Ju Kuo, Ya-Chu Hsu, Sin-Tian Wang, Bang-Yu Liou, Serene Boon-Yuean Lim, Yi-Wei Chen, Chang-Shi Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
Caenorhabditis elegans
iglr-2
innate immunity
p38 MAPK pathway
enterohemorrhagic Escherichia coli
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.561337/full

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