Global perspectives on bipolar disorder treatment: in-depth comparative analysis of international guidelines for medication selection
Background Bipolar disorder, a chronic mental health condition characterised by fluctuations in mood, energy and functionality, affects millions of individuals worldwide. Its management requires a comprehensive approach, and, as such, treatment guidelines have a pivotal role in guiding clinicians to...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2024-05-01
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| Series: | BJPsych Open |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2056472424000279/type/journal_article |
| _version_ | 1827290271512002560 |
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| author | Ji Hyun Park Kaveesha Fernando Youngja Hwang Park Esther O. Park |
| author_facet | Ji Hyun Park Kaveesha Fernando Youngja Hwang Park Esther O. Park |
| author_sort | Ji Hyun Park |
| collection | DOAJ |
| description | Background
Bipolar disorder, a chronic mental health condition characterised by fluctuations in mood, energy and functionality, affects millions of individuals worldwide. Its management requires a comprehensive approach, and, as such, treatment guidelines have a pivotal role in guiding clinicians to alleviate symptoms, prevent relapse and enhance overall patient well-being. However, the treatment landscape is far from homogenous, with significant variations existing across different countries.
Aims
This study aimed to explore and compare treatment guidelines for bipolar disorder in various regions, shedding light on the factors that influence therapeutic approaches and thus offering insights that could contribute to the ongoing refinement of evidence-based practices in management.
Method
The study explores various international treatment guidelines for bipolar disorder that have been updated after 2014. Guidelines from the UK, Canada, Australia/New Zealand, South Korea and the International College of Neuropsychopharmacology are scrutinised to identify factors contributing to the observed differences among them.
Results
The variations in recommended drugs across guidelines arise from the approaches employed in guideline development – whether relying on expert consensus or meta-analysis results. Timing disparities in conducting these analyses and the selection of studies also exert influence. Moreover, differences in metabolic enzymes among diverse races and the health policies implemented by individual nations play a significant part in shaping these differences.
Conclusion
The primary hindrance to consistent treatment conclusions lies in the scarcity of high-quality research results, leading to variations in guidelines. Enhancing evidence-based recommendations necessitates the undertaking of large-scale studies dedicated to assessing treatments for bipolar disorder.
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| first_indexed | 2024-04-24T12:13:41Z |
| format | Article |
| id | doaj.art-8363f53476794655bd06506e9fd154cd |
| institution | Directory Open Access Journal |
| issn | 2056-4724 |
| language | English |
| last_indexed | 2024-04-24T12:13:41Z |
| publishDate | 2024-05-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | BJPsych Open |
| spelling | doaj.art-8363f53476794655bd06506e9fd154cd2024-04-08T08:54:17ZengCambridge University PressBJPsych Open2056-47242024-05-011010.1192/bjo.2024.27Global perspectives on bipolar disorder treatment: in-depth comparative analysis of international guidelines for medication selectionJi Hyun Park0https://orcid.org/0000-0002-6705-2193Kaveesha Fernando1Youngja Hwang Park2Esther O. Park3College of Pharmacy, Duksung Women's University, Seoul, Republic of KoreaCollege of Pharmacy, Duksung Women's University, Seoul, Republic of KoreaOmics Research Center, Korea University, Sejong, Republic of Korea; and Metabolomics Laboratory, College of Pharmacy, Korea University, Sejong, Republic of KoreaSchool of Nursing, College of Public Health, George Mason University, Fairfax, Virginia, USABackground Bipolar disorder, a chronic mental health condition characterised by fluctuations in mood, energy and functionality, affects millions of individuals worldwide. Its management requires a comprehensive approach, and, as such, treatment guidelines have a pivotal role in guiding clinicians to alleviate symptoms, prevent relapse and enhance overall patient well-being. However, the treatment landscape is far from homogenous, with significant variations existing across different countries. Aims This study aimed to explore and compare treatment guidelines for bipolar disorder in various regions, shedding light on the factors that influence therapeutic approaches and thus offering insights that could contribute to the ongoing refinement of evidence-based practices in management. Method The study explores various international treatment guidelines for bipolar disorder that have been updated after 2014. Guidelines from the UK, Canada, Australia/New Zealand, South Korea and the International College of Neuropsychopharmacology are scrutinised to identify factors contributing to the observed differences among them. Results The variations in recommended drugs across guidelines arise from the approaches employed in guideline development – whether relying on expert consensus or meta-analysis results. Timing disparities in conducting these analyses and the selection of studies also exert influence. Moreover, differences in metabolic enzymes among diverse races and the health policies implemented by individual nations play a significant part in shaping these differences. Conclusion The primary hindrance to consistent treatment conclusions lies in the scarcity of high-quality research results, leading to variations in guidelines. Enhancing evidence-based recommendations necessitates the undertaking of large-scale studies dedicated to assessing treatments for bipolar disorder. https://www.cambridge.org/core/product/identifier/S2056472424000279/type/journal_articleBipolar disorderguidelinetreatmentpharmacotherapycomparison |
| spellingShingle | Ji Hyun Park Kaveesha Fernando Youngja Hwang Park Esther O. Park Global perspectives on bipolar disorder treatment: in-depth comparative analysis of international guidelines for medication selection BJPsych Open Bipolar disorder guideline treatment pharmacotherapy comparison |
| title | Global perspectives on bipolar disorder treatment: in-depth comparative analysis of international guidelines for medication selection |
| title_full | Global perspectives on bipolar disorder treatment: in-depth comparative analysis of international guidelines for medication selection |
| title_fullStr | Global perspectives on bipolar disorder treatment: in-depth comparative analysis of international guidelines for medication selection |
| title_full_unstemmed | Global perspectives on bipolar disorder treatment: in-depth comparative analysis of international guidelines for medication selection |
| title_short | Global perspectives on bipolar disorder treatment: in-depth comparative analysis of international guidelines for medication selection |
| title_sort | global perspectives on bipolar disorder treatment in depth comparative analysis of international guidelines for medication selection |
| topic | Bipolar disorder guideline treatment pharmacotherapy comparison |
| url | https://www.cambridge.org/core/product/identifier/S2056472424000279/type/journal_article |
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