The 100th anniversary of pH (1909-2009). Negative logarithms for measuring hydrogen ions: are they essential in medicine? Part I

Introduction: It has been 100 years since the concept of pH (1909-2009) was ‘‘invented’’ by the Danish chemist-mathematician Søren Peter Lauritz Sørensen (1868-1939) in the chemistry laboratories of the Carlsberg Brewery in Copenhagen. The anniversary provides an opportunity to examine the crucial i...

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Main Authors: Francesco Sgambato, Sergio Prozzo, Ester Sgambato, Rosa Sgambato, Luca Milano
Format: Article
Language:English
Published: PAGEPress Publications 2013-03-01
Series:Italian Journal of Medicine
Subjects:
Online Access:http://www.italjmed.org/index.php/ijm/article/view/120
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author Francesco Sgambato
Sergio Prozzo
Ester Sgambato
Rosa Sgambato
Luca Milano
author_facet Francesco Sgambato
Sergio Prozzo
Ester Sgambato
Rosa Sgambato
Luca Milano
author_sort Francesco Sgambato
collection DOAJ
description Introduction: It has been 100 years since the concept of pH (1909-2009) was ‘‘invented’’ by the Danish chemist-mathematician Søren Peter Lauritz Sørensen (1868-1939) in the chemistry laboratories of the Carlsberg Brewery in Copenhagen. The anniversary provides an opportunity to examine the crucial importance in human life of acid-base balance. <br />Materials and methods: The authors review the historical process that led to the creation of the pH scale, with citation of passages from the original work of Sørensen published 100 years ago. This is followed by a critical analysis of the debate regarding the use of logarithmstomeasure hydrogen ion concentrations based on data from scientific papers published over the past 50 years (1960-2010). <br />Results and discussion: The authors conclude that the concept of acid-base balance can be approached and taught in a simpler, more exciting, and even pleasant fashion without using the infamous and abstruse Henderson-Hasselbalch equation. The whole rationale underlying the understanding and clinical application of this vital topic is clearly and unquestionably inherent simpler, more manageable formula introduced by Henderson (without logs), which is useful and quite adequate for use in medical education.
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spelling doaj.art-8364e52f3a384e2ebd80d48cfae9fce92023-12-03T05:27:10ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522013-03-015314715510.4081/itjm.2011.14794The 100th anniversary of pH (1909-2009). Negative logarithms for measuring hydrogen ions: are they essential in medicine? Part IFrancesco SgambatoSergio ProzzoEster SgambatoRosa SgambatoLuca MilanoIntroduction: It has been 100 years since the concept of pH (1909-2009) was ‘‘invented’’ by the Danish chemist-mathematician Søren Peter Lauritz Sørensen (1868-1939) in the chemistry laboratories of the Carlsberg Brewery in Copenhagen. The anniversary provides an opportunity to examine the crucial importance in human life of acid-base balance. <br />Materials and methods: The authors review the historical process that led to the creation of the pH scale, with citation of passages from the original work of Sørensen published 100 years ago. This is followed by a critical analysis of the debate regarding the use of logarithmstomeasure hydrogen ion concentrations based on data from scientific papers published over the past 50 years (1960-2010). <br />Results and discussion: The authors conclude that the concept of acid-base balance can be approached and taught in a simpler, more exciting, and even pleasant fashion without using the infamous and abstruse Henderson-Hasselbalch equation. The whole rationale underlying the understanding and clinical application of this vital topic is clearly and unquestionably inherent simpler, more manageable formula introduced by Henderson (without logs), which is useful and quite adequate for use in medical education.http://www.italjmed.org/index.php/ijm/article/view/120pHHistory of pHCentenary of pHAcid-base balanceEquation of HendersonEquation of Henderson- HasselbalchLogarithms in Medicine.
spellingShingle Francesco Sgambato
Sergio Prozzo
Ester Sgambato
Rosa Sgambato
Luca Milano
The 100th anniversary of pH (1909-2009). Negative logarithms for measuring hydrogen ions: are they essential in medicine? Part I
Italian Journal of Medicine
pH
History of pH
Centenary of pH
Acid-base balance
Equation of Henderson
Equation of Henderson- Hasselbalch
Logarithms in Medicine.
title The 100th anniversary of pH (1909-2009). Negative logarithms for measuring hydrogen ions: are they essential in medicine? Part I
title_full The 100th anniversary of pH (1909-2009). Negative logarithms for measuring hydrogen ions: are they essential in medicine? Part I
title_fullStr The 100th anniversary of pH (1909-2009). Negative logarithms for measuring hydrogen ions: are they essential in medicine? Part I
title_full_unstemmed The 100th anniversary of pH (1909-2009). Negative logarithms for measuring hydrogen ions: are they essential in medicine? Part I
title_short The 100th anniversary of pH (1909-2009). Negative logarithms for measuring hydrogen ions: are they essential in medicine? Part I
title_sort 100th anniversary of ph 1909 2009 negative logarithms for measuring hydrogen ions are they essential in medicine part i
topic pH
History of pH
Centenary of pH
Acid-base balance
Equation of Henderson
Equation of Henderson- Hasselbalch
Logarithms in Medicine.
url http://www.italjmed.org/index.php/ijm/article/view/120
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