Cytologic and Clinical Evaluation of Human Papillomavirus in Women Underwent Routine Gynecologic Examination
OBJECTIVE: To determine the frequency of Human Papillomavirus infection in routine gynecologic examination and to detect whether there is a relationship between the presence of Human Papilloma Virus and cytologic and gynecological findings. STUDY DESIGN: Four hundred women applying to Gynecology out...
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| Format: | Article |
| Language: | English |
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Medical Network
2009-08-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/410 |
| _version_ | 1797908848980262912 |
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| author | Zehra Safi Öz Şayeste Demirezen Gamze Mocan Kuzey Mehmet Sinan Beksaç Şemsettin Ustaçelebi |
| author_facet | Zehra Safi Öz Şayeste Demirezen Gamze Mocan Kuzey Mehmet Sinan Beksaç Şemsettin Ustaçelebi |
| author_sort | Zehra Safi Öz |
| collection | DOAJ |
| description | OBJECTIVE: To determine the frequency of Human Papillomavirus infection in routine gynecologic examination and to detect whether there is a relationship between the presence of Human Papilloma Virus and cytologic and gynecological findings.
STUDY DESIGN: Four hundred women applying to Gynecology outpatient clinic for routine gynecologic examination were included. Conventional Pap smears of 400 patients were stained by Papanicolaou technique and examined cytologically. HPV DNA was detected by in-house PCR . Also HPV positive samples were evaluated for HPV 16 and 18 by same method.
RESULTS: Eleven (2.75%) of 400 women were HPV DNA (+). Two of which were type 16 and 18 and one of which was type 18. Nuclear membrane irregularity, hyperchromatism, koilocytotic cell, vacuolisation and post partum period corralated with HPV infection (p <0.05).
CONCLUSION: Pap smear examination is a value of detection of cellular changes belonging Human Papillomavirus and if in this examination it is need to, these patients refer to Human Papillomavirus DNA screening it would be more cost effective. |
| first_indexed | 2024-04-10T10:58:54Z |
| format | Article |
| id | doaj.art-8364fd9101e644ae9681b6a5ddf0e5ae |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T10:58:54Z |
| publishDate | 2009-08-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-8364fd9101e644ae9681b6a5ddf0e5ae2023-02-15T16:19:46ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512009-08-01152342Cytologic and Clinical Evaluation of Human Papillomavirus in Women Underwent Routine Gynecologic ExaminationZehra Safi Öz0Şayeste Demirezen1Gamze Mocan Kuzey2Mehmet Sinan Beksaç3Şemsettin Ustaçelebi4Zonguldak Karaelmas University, Faculty of Medicine, Department of Medical Biology, ZonguldakHacettepe University, Faculty of Science, Department of Biology, AnkaraHacettepe University, Faculty of Medicine, Department of Pathology, AnkaraHacettepe University, Faculty of Medicine, Department of Obstetrics and Gynecology, AnkaraHacettepe University, Faculty of Medicine, Department of Microbiology and Clinic Microbiology, AnkaraOBJECTIVE: To determine the frequency of Human Papillomavirus infection in routine gynecologic examination and to detect whether there is a relationship between the presence of Human Papilloma Virus and cytologic and gynecological findings. STUDY DESIGN: Four hundred women applying to Gynecology outpatient clinic for routine gynecologic examination were included. Conventional Pap smears of 400 patients were stained by Papanicolaou technique and examined cytologically. HPV DNA was detected by in-house PCR . Also HPV positive samples were evaluated for HPV 16 and 18 by same method. RESULTS: Eleven (2.75%) of 400 women were HPV DNA (+). Two of which were type 16 and 18 and one of which was type 18. Nuclear membrane irregularity, hyperchromatism, koilocytotic cell, vacuolisation and post partum period corralated with HPV infection (p <0.05). CONCLUSION: Pap smear examination is a value of detection of cellular changes belonging Human Papillomavirus and if in this examination it is need to, these patients refer to Human Papillomavirus DNA screening it would be more cost effective.http://gorm.com.tr/index.php/GORM/article/view/410Human Papillomavirus, Polymerase chain reaction (PCR), Pap smear, Koilocytotic cell |
| spellingShingle | Zehra Safi Öz Şayeste Demirezen Gamze Mocan Kuzey Mehmet Sinan Beksaç Şemsettin Ustaçelebi Cytologic and Clinical Evaluation of Human Papillomavirus in Women Underwent Routine Gynecologic Examination Gynecology Obstetrics & Reproductive Medicine Human Papillomavirus, Polymerase chain reaction (PCR), Pap smear, Koilocytotic cell |
| title | Cytologic and Clinical Evaluation of Human Papillomavirus in Women Underwent Routine Gynecologic Examination |
| title_full | Cytologic and Clinical Evaluation of Human Papillomavirus in Women Underwent Routine Gynecologic Examination |
| title_fullStr | Cytologic and Clinical Evaluation of Human Papillomavirus in Women Underwent Routine Gynecologic Examination |
| title_full_unstemmed | Cytologic and Clinical Evaluation of Human Papillomavirus in Women Underwent Routine Gynecologic Examination |
| title_short | Cytologic and Clinical Evaluation of Human Papillomavirus in Women Underwent Routine Gynecologic Examination |
| title_sort | cytologic and clinical evaluation of human papillomavirus in women underwent routine gynecologic examination |
| topic | Human Papillomavirus, Polymerase chain reaction (PCR), Pap smear, Koilocytotic cell |
| url | http://gorm.com.tr/index.php/GORM/article/view/410 |
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