Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis

Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis

While the anti-inflammatory activities of Eriodictyol, a plant-derived flavonoid is well-known, reports on its anti-cancer efficacy and selective cytotoxicity in cancer cells are still emerging. However, little is known regarding its mechanism of selective anti-cancer activities. Here, we show the m...

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Bibliographic Details
Main Authors: Shibjyoti Debnath, Abhisek Sarkar, Dipanwita Das Mukherjee, Subha Ray, Barun Mahata, Tarun Mahata, Pravat K. Parida, Troyee Das, Rupak Mukhopadhyay, Zhumur Ghosh, Kaushik Biswas
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Translational Oncology
Subjects:
Flavonoids
CRISPR-Cas9
Cell death
Tumorigenesis
Selective cytotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523322000924

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