Dosimetric Evaluation of the Treatment Plan on Indigenous Heterogeneous Phantoms using Analytical Anisotropic Algorithm and Acuros-XB Algorithm for Different Photon Energies

Background: Modern radiotherapy techniques are using advanced algorithms; however, phantoms used for quality assurance have homogeneous density; accordingly, the development of heterogeneous phantom mimicking human body sites is imperative to examine variation between planned and delivered doses. Ob...

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Main Authors: Vinod Kumar Gangwar, Om Prakash Gurjar, Lalit Kumar, Avinash Agarwal, Vineet Kumar Mishra, Surendra Prasad Mishra, Saket Pandey
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2022-06-01
Series:Journal of Biomedical Physics and Engineering
Subjects:
Online Access:https://jbpe.sums.ac.ir/article_48340_58b86ff782ebeb39a902762115a4565a.pdf
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author Vinod Kumar Gangwar
Om Prakash Gurjar
Lalit Kumar
Avinash Agarwal
Vineet Kumar Mishra
Surendra Prasad Mishra
Saket Pandey
author_facet Vinod Kumar Gangwar
Om Prakash Gurjar
Lalit Kumar
Avinash Agarwal
Vineet Kumar Mishra
Surendra Prasad Mishra
Saket Pandey
author_sort Vinod Kumar Gangwar
collection DOAJ
description Background: Modern radiotherapy techniques are using advanced algorithms; however, phantoms used for quality assurance have homogeneous density; accordingly, the development of heterogeneous phantom mimicking human body sites is imperative to examine variation between planned and delivered doses. Objective: This study aimed to analyze the accuracy of planned dose by different algorithms using indigenously developed heterogeneous thoracic phantom (HT). Material and Methods: In this experimental study, computed tomography (CT) of HT was done, and the density of different parts was measured. The plan was generated on CT images of HCP with 6 and 15 Megavoltage (MV) photon beams using different treatment techniques, including three-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT). Plans were delivered by the linear accelerator, and the dose was measured using the ion chamber (IC) placed in HT; planned and measured doses were compared. Results: Density patterns for different parts of the fabricated phantom, including rib, spine, scapula, lung, chest wall, and heart were 1.849, 1.976, 1.983, 0.173, 0.855, and 0.833 g/cc, respectively. Variation between planned and IC estimated doses with the tolerance (±5%) for all photon energies using different techniques. Acuros-XB (AXB) showed a slightly higher variation between computed and IC estimated doses using HCP compared to the analytical anisotropic algorithm (AAA). Conclusion: The indigenous heterogeneous phantom can accurately simulate the dosimetric scenario for different algorithms (AXB or AAA) and be also utilized for routine patient-specific QA.
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spelling doaj.art-8367f840484a4660864da7507e80bd462022-12-22T00:35:19ZengShiraz University of Medical SciencesJournal of Biomedical Physics and Engineering2251-72002022-06-0112323724410.31661/jbpe.v0i0.2012-124648340Dosimetric Evaluation of the Treatment Plan on Indigenous Heterogeneous Phantoms using Analytical Anisotropic Algorithm and Acuros-XB Algorithm for Different Photon EnergiesVinod Kumar Gangwar0Om Prakash Gurjar1Lalit Kumar2Avinash Agarwal3Vineet Kumar Mishra4Surendra Prasad Mishra5Saket Pandey6PhD Candidate, Department of Physics, M.J.P. Rohilkhand University, Bareilly Uttar Pradesh, IndiaPhD, Government Cancer Hospital, Mahatma Gandhi Memorial Medical College, Indore-452001, IndiaPhD, Department of Applied Science & Humanities, Dr. A.P.J Abdul Kalam Technical University, Lucknow, IndiaPhD, Department of Physics Bareilly College Bareilly, Uttar Pradesh, IndiaMSc, Apollomedics Hospital, Lucknow, IndiaPhD, Department of Radiation Oncology, Ram Manohar Lohia Medical sciences Lucknow, IndiaMD, Medical Physics Division & amp Department of Radiation Oncology, Apollomedics Hospital, Lucknow, IndiaBackground: Modern radiotherapy techniques are using advanced algorithms; however, phantoms used for quality assurance have homogeneous density; accordingly, the development of heterogeneous phantom mimicking human body sites is imperative to examine variation between planned and delivered doses. Objective: This study aimed to analyze the accuracy of planned dose by different algorithms using indigenously developed heterogeneous thoracic phantom (HT). Material and Methods: In this experimental study, computed tomography (CT) of HT was done, and the density of different parts was measured. The plan was generated on CT images of HCP with 6 and 15 Megavoltage (MV) photon beams using different treatment techniques, including three-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT). Plans were delivered by the linear accelerator, and the dose was measured using the ion chamber (IC) placed in HT; planned and measured doses were compared. Results: Density patterns for different parts of the fabricated phantom, including rib, spine, scapula, lung, chest wall, and heart were 1.849, 1.976, 1.983, 0.173, 0.855, and 0.833 g/cc, respectively. Variation between planned and IC estimated doses with the tolerance (±5%) for all photon energies using different techniques. Acuros-XB (AXB) showed a slightly higher variation between computed and IC estimated doses using HCP compared to the analytical anisotropic algorithm (AAA). Conclusion: The indigenous heterogeneous phantom can accurately simulate the dosimetric scenario for different algorithms (AXB or AAA) and be also utilized for routine patient-specific QA.https://jbpe.sums.ac.ir/article_48340_58b86ff782ebeb39a902762115a4565a.pdfalgorithmscomputed tomographyhuman bodylung phantomsvolumetric-modulated arc therapyribs
spellingShingle Vinod Kumar Gangwar
Om Prakash Gurjar
Lalit Kumar
Avinash Agarwal
Vineet Kumar Mishra
Surendra Prasad Mishra
Saket Pandey
Dosimetric Evaluation of the Treatment Plan on Indigenous Heterogeneous Phantoms using Analytical Anisotropic Algorithm and Acuros-XB Algorithm for Different Photon Energies
Journal of Biomedical Physics and Engineering
algorithms
computed tomography
human body
lung phantoms
volumetric-modulated arc therapy
ribs
title Dosimetric Evaluation of the Treatment Plan on Indigenous Heterogeneous Phantoms using Analytical Anisotropic Algorithm and Acuros-XB Algorithm for Different Photon Energies
title_full Dosimetric Evaluation of the Treatment Plan on Indigenous Heterogeneous Phantoms using Analytical Anisotropic Algorithm and Acuros-XB Algorithm for Different Photon Energies
title_fullStr Dosimetric Evaluation of the Treatment Plan on Indigenous Heterogeneous Phantoms using Analytical Anisotropic Algorithm and Acuros-XB Algorithm for Different Photon Energies
title_full_unstemmed Dosimetric Evaluation of the Treatment Plan on Indigenous Heterogeneous Phantoms using Analytical Anisotropic Algorithm and Acuros-XB Algorithm for Different Photon Energies
title_short Dosimetric Evaluation of the Treatment Plan on Indigenous Heterogeneous Phantoms using Analytical Anisotropic Algorithm and Acuros-XB Algorithm for Different Photon Energies
title_sort dosimetric evaluation of the treatment plan on indigenous heterogeneous phantoms using analytical anisotropic algorithm and acuros xb algorithm for different photon energies
topic algorithms
computed tomography
human body
lung phantoms
volumetric-modulated arc therapy
ribs
url https://jbpe.sums.ac.ir/article_48340_58b86ff782ebeb39a902762115a4565a.pdf
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